Person: OTÇU TEMUR, HAFİZE
Now showing 1 - 10 of 13
- PublicationMetadata onlyDevelopment of Antiarrhythmic Therapy-Resistant Ventricular Tachycardia, Ventricular Fibrillation, and Premature Ventricular Contractions in a 15-Year-Old Patient(2020-09-01T00:00:00Z) Yozgat, Can Yilmaz; YEŞİLBAŞ, Osman; İŞCAN, AKIN; YURTSEVER, İsmail; OTÇU TEMUR, Hafize; BAYRAMOVA, NİGAR; ERGÜN, GÖKÇE; TEKİN, NUR; YOZGAT, Yılmaz; YEŞİLBAŞ, OSMAN; İŞCAN, AKIN; YURTSEVER, İSMAİL; OTÇU TEMUR, HAFİZE; BAYRAMOVA, NİGAR; ERGÜN, GÖKÇE; TEKİN, NUR; YOZGAT, YILMAZSudden cardiac arrest (SCA) is the sudden cessation of regular cardiac activity so that the victim becomes unresponsive, with no signs of circulation and no normal breathing. Asystole, ventricular tachycardia (VT), ventricular fibrillation (VF), and pulseless electrical activity are the underlying rhythm disturbances in the pediatric age group. If appropriate interventions (cardiopulmonary resuscitation-CPR and/or defibrillation or cardioversion) are not performed rapidly, this condition progresses to sudden death. There have not been many reported cases of the approach and treatment of cardiac arrhythmias after SCA. Herein, we would like to report a case of a 15-year-old female patient with dilated cardiomyopathy (DCM) who was admitted to our clinic a year ago, and while her left ventricular systolic functions were improved, SCA suddenly occurred. Since the SCA event occurred in another city, intravenous treatment of amiodarone was done immediately and was switch to continuous infusion dose of amiodarone until the patient arrived at our institution-s pediatric intensive care unit (PICU) 3hours later. During the patient-s 20-day PICU hospitalization, she developed pulseless VT and VF from time to time. The patient-s pulseless VT and VF attacks were brought under control by the use of a defibrillator and added antiarrhythmic drugs (amiodarone, flecainide, esmolol, and propafenone). Intriguingly, therapy-resistance bigeminy with premature ventricular contractions (PVCs) continued despite all these treatments. The patient did not have adequate blood pressure measured by invasive arterial blood pressure monitoring while having bigeminy PVCs. The intermittent bigeminy PVCs ameliorated rapidly after intermittent boluses of lidocaine. In the end, multiple antiarrhythmic therapies and intermittent bolus lidocaine doses were enough to bring her cardiac arrhythmias after SCA under control. This case illustrates that malign PVC-s should be taken very seriously, since they may predispose to the development of VT or VF. Also, this case highlights the importance of close vigilance of arterial pressure tracings of patients with bigeminy PVCs which develop after SCA and should not be accepted as normal.
- PublicationMetadata onlySudden Cardiac Arrest and Malignant Ventricular Tachycardia in an 8-Year-Old Pediatric Patient Who Has Hemolytic Uremic Syndrome Associated with Shiga Toxin-Producing Escherichia coli(2020-12-01T00:00:00Z) YEŞİLBAŞ, Osman; Yozgat, Can Yilmaz; AKINCI, NURVER; TALEBAZADEH, FARAZ; JAFAROV, UZEYİR; GÜNEY, ABDURRAHMAN ZARİF; OTÇU TEMUR, Hafize; YOZGAT, YILMAZ; YEŞİLBAŞ, OSMAN; AKINCI, NURVER; TALEBAZADEH, FARAZ; JAFAROV, UZEYİR; GÜNEY, ABDURRAHMAN ZARİF; OTÇU TEMUR, HAFİZE; YOZGAT, YILMAZGastrointestinal, neurological, pancreatic, hepatic, and cardiac dysfunction are extrarenal manifestations of hemolytic uremic syndrome associated with Shiga toxinproducing Escherichia coli (STEC-HUS). The most frequent cause of death for STECHUS is related to the central nervous system and cardiovascular system. Cardiac-origin deaths are predominantly related to thrombotic microangiopathy-induced ischemia and the immediate development of circulatory collapse. STEC-HUS cardiac related deaths in children are rare with only sporadic cases reported. In our literature search, we did not come across any pediatric case report about STEC-HUS causing sudden cardiac arrest and malignant ventricular tachycardia (VT). Herein, we report the case of an 8-year-old female child with a typical clinical manifestation of STEC-HUS. On the seventh day of pediatric intensive care unit admission, the patient had a sudden cardiac arrest, requiring resuscitation for 10minutes. The patient had return of spontaneous circulation with severe monomorphic pulsed malignant VT. Intravenous treatment with lidocaine, amiodarone and magnesium sulfate were promptly initiated, and we administered multiple synchronized cardioversions, but VT persisted. Furthermore, we were not able to ameliorate her refractory circulation insufficiency by advanced cardiopulmonary resuscitation. Thus, inevitably, the patient lost her life. This case illustrates the need for aggressive management and the dilemma that pediatric critical care specialists, cardiologists, and nephrologists have to face when dealing with STECHUS that is worsened by a sudden cardiac arrest accompanied with VT.
- PublicationOpen AccessComparison of MRI Features of Invasive Pleomorphic and Classical Lobular Carcinoma: Differentiation Is Possible?(2022-01-01T00:00:00Z) YILMAZ, TEMEL FATİH; OTÇU TEMUR, HAFİZE; SARI, LÜTFULLAH; GÜCİN, ZÜHAL; GÜLTEKİN, MEHMET ALİ; ÇELİK YABUL, FATMA; TOPRAK, HÜSEYİN; YILDIZ, ŞEYMA; YILMAZ, TEMEL FATİH; OTÇU TEMUR, HAFİZE; SARI, LÜTFULLAH; GÜCİN, ZÜHAL; GÜLTEKİN, MEHMET ALİ; ÇELİK YABUL, FATMA; TOPRAK, HÜSEYİN; YILDIZ, ŞEYMATo evaluate breast MRI and DWI and demographic features of pleomorphic invasive lobular carcinoma (pILC) and classic invasive lobular carcinoma (cILC). Invasive lobular (ILC) is the second most common breast malignancy after invasive ductal carcinoma (IDC) and constitutes the 8-14% of all invasive breast cancers. ILC morphologically can be classified into the classic, alveolar, solid, tubulolobular, and pleomorphic subtypes according to WHO. This study was performed retrospectively. The MRI and demographic features of 18 patients with 23 pILC were compared with those 22 consecutive patients with 27 cILC. There was no significant difference in demographic features of patients, MR appearance, kinetics, and ADC values between two groups. pILC, an aggressive subtype of ILC, cannot be differentiated from cILC with breast MRI.
- PublicationMetadata onlyImportance of pre-treatment Fractional Anisotropy value in predicting volumetric response in patients with meningioma treated with Gamma Knife Radiosurgery(2021-09-01T00:00:00Z) Çeşme, Dilek Hacer; Alkan, Alpay; Sarı, Lutfullah; Çelik Yabul, Fatma; Otçu Temur, Hafize; Aykan, Mahmut Esat; Seyithanaoglu, Mehmet Hakan; Hatiboğlu, Mustafa Aziz; ÇELİK YABUL, FATMA; OTÇU TEMUR, HAFİZE; HATİBOĞLU, MUSTAFA AZİZ
- PublicationMetadata onlyDevelopment of Myocardial Infarction in a 12-Year-Old Female after the Use of Inhaled Salbutamol(2020-12-01T00:00:00Z) Yozgat, Can Yilmaz; UZUNER, SELÇUK; OTÇU TEMUR, Hafize; ERGÖR, Serap Nur; GULİYEVA, AYNUR; Tahaoglu, Irmak; Coban, Senay; YOZGAT, YILMAZ; UZUNER, SELÇUK; OTÇU TEMUR, HAFİZE; ERGÖR, SERAP NUR; GULİYEVA, AYNUR; YOZGAT, YILMAZAnomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) accounts for 0.023% of all cases reported in pediatric patients. According to literature, only a handful of ALCAPA patients are able to reach adulthood. Clinical manifestations of ALCAPA range from fatigue during exercise to sudden death in adulthood. Herein, we described a 12-year-old symptomatic patient with ALCAPA who had severe chest pain after using salbutamol treatment for presumed asthma. ALCAPA is one of the curable versions of myocardial ischemia and infarction in childhood. Due to clinical findings in conjunction with electrocardiogram and echocardiography, a computed tomography scan with coronary angiography was performed and the diagnosis of ALCAPA was confirmed. We presented this case because ALCAPA-related myocardial ischemia and infarction in children are rare with only sporadic cases reported. This case illustrated the need for close monitoring and surgery as the best treatment for ALCAPA associated with myocardial infarction.
- PublicationOpen AccessEpicardial adipose tissue volume predicts long term major adverse cardiovascular events in patients with Type 2 diabetes(2021-03-01T00:00:00Z) Uygur, Begum; Celik, Omer; Demir, Ali Riza; Karakayali, Muammer; Arslan, Cagdas; OTÇU TEMUR, Hafize; Alis, Deniz; Yildirim, Ceren; Corekcioglu, Busra; Erturk, Mehmet; OTÇU TEMUR, HAFİZEObjective: Epicardial adipose tissue (EAT) is a metabolically active visceral fat depot that plays an important role in coronary atherosclerosis. In this study, our aim was to investigate the relationship between long-term major adverse cardiovascular events (MACEs) and EAT volume detected by coronary computed tomography angiography (CCTA) in patients with Type 2 diabetes mellitus (T2-DM) without previous coronary events. Methods: A total of 127 patients with diabetes who underwent CCTA between 2012 and 2014 were enrolled retrospectively. The study population was divided into 2 groups according to whether they experienced or did not experience MACE, which was defined as cardiac death, non-fatal myocardial infarction or unstable angina requiring hospitalization, coronary revascularizations (percutaneous coronary intervention or coronary artery bypass grafting surgery), heart failure, peripheral arterial disease, or ischemic stroke. In both groups, EAT volumes were measured by CCTA. Results: During 60±7 months follow-up period, 22 participants experienced MACEs. Data were evaluated with univariate and multivariate analyses and receiver operating characteristic (ROC) analysis. Age, male sex, coronary artery disease, hemoglobin A1c, glucose, creatinine, C- reactive protein, and cholesterol levels were found to be associated with MACE. EAT volume (odds ratio [OR]: 1.027; 95% confidence interval [CI]: 1.010‒1.044, p=0.002) and low-density lipoprotein (OR: 1.015; 95% CI: 1.000‒1.030, p=0.050) were found to be independent predictors for MACE. ROC analysis indicated that EAT volumes >123.2 mL had a 72.7% sensitivity and a 77.1% specificity for predicting long-term MACE in patients with T2-DM (area under the curve: 0.820; 95% CI: 0.733-0.908). Conclusion: EAT volume is an independent predictor of long-term MACE in patients with T2-DM without previous coronary events. EAT volume may be used additionally in risk stratification for MACE besides the well-known vascular risk factors in patients with T2-DM.
- PublicationOpen AccessA Rare Cause of Pulmonary Hypertension in a 4-Year-Old Toddler: Association of Cor Triatriatum Sinister and Pulmonary Arteriovenous Malformation(2020-11-01T00:00:00Z) Yozgat, Can Yilmaz; ÇAKIR, Erkan; YAZAN, HAKAN; OTÇU TEMUR, Hafize; YAKUT, KAHRAMAN; YOZGAT, YILMAZ; ÇAKIR, ERKAN; YAZAN, HAKAN; OTÇU TEMUR, HAFİZE; YAKUT, KAHRAMAN; YOZGAT, YILMAZCor triatriatum sinister is a rare congenital cardiac anomaly. The anomaly is caused by a fibromuscular membrane that divides the left atrium into two cavities. This membrane can lead to the obstruction of left atrial flow and also create pulmonary venous hypertension. Pulmonary arteriovenous malformation (PAVM) is notorious for its aberrant blood flow between the pulmonary arteries and veins. Herein, we report a case of a 4-year-old toddler who had a unique form of pulmonary hypertension presenting with cor triatriatum sinister and diffuse PAVM. After the surgical treatment of cor triatriatum sinister, both pulmonary arteriovenous malformation and pulmonary hypertension disappeared.
- PublicationMetadata onlyBalanced Double Aortic Arch Causing Persistent Respiratory Symptoms Mimicking Asthma in an Infant(2020-09-01T00:00:00Z) OTÇU TEMUR, Hafize; Yozgat, Can Yilmaz; UZUNER, SELÇUK; Ugurlucan, Murat; YAZAN, HAKAN; ÇAKIR, Erkan; YOZGAT, Yılmaz; OTÇU TEMUR, HAFİZE; UZUNER, SELÇUK; YAZAN, HAKAN; ÇAKIR, ERKAN; YOZGAT, YILMAZDouble aortic arch (DAA) is a common form of complete vascular ring. The state of the condition leads to upper airway impediment and compression of the esophagus. A balanced DAA is an extremely rare anomaly. The anatomical aberration cannot be easily diagnosed with echocardiography when an infant has chronic respiratory distress. Herein, we present the case of an 11-month-old girl who had chronic respiratory distress and a balanced DAA.
- PublicationMetadata onlyAcute Myocarditis and Eculizumab Caused Severe Cholestasis in a 17-Month-Old Child Who Has Hemolytic Uremic Syndrome Associated with Shiga Toxin-Producing Escherichia coli(2021-09-01T00:00:00Z) YEŞİLBAŞ, Osman; Yozgat, Can Yilmaz; AKINCI, NURVER; SÖNMEZ, ŞİRİN; TEKİN, ESER; TALEBAZADEH, FARAZ; JAFAROV, UZEYİR; OTÇU TEMUR, Hafize; YOZGAT, YILMAZ; YEŞİLBAŞ, OSMAN; AKINCI, NURVER; SÖNMEZ, ŞİRİN; TEKİN, ESER; TALEBAZADEH, FARAZ; JAFAROV, UZEYİR; OTÇU TEMUR, HAFİZE; YOZGAT, YILMAZCardiovascular involvement is uncommon in pediatric patients with hemolytic uremic syndrome associated with Shiga toxin-producing Escherichia coli (STEC-HUS). In this case report we presented a case of 17-month-old toddler who had a sporadic type of STEC-HUS complicated by acute myocarditis. The patient was successfully treated by a single dose of eculizumab after six doses of therapeutic plasma exchange (TPE) were inefficient to prevent the cardiac complication. Hepatotoxicity was observed after a single dose of eculizumab. Hepatic and cholestatic enzyme levels slowly returned to normal within 6 months. To the best of our knowledge, this is the first case of myocarditis/cardiomyopathy treated with eculizumab in STEC-HUS. This case illustrates the need for vigilance regarding myocardial involvement and eculizumab-induced hepatotoxicity in STEC-HUS.
- PublicationMetadata onlyShort-term efficacy of ORS formulation and propranolol regimen in children with POTS(2020-08-01T00:00:00Z) YOZGAT, Yılmaz; OTÇU TEMUR, Hafize; Coban, Senay; Oner, Taliha; Karaarslan, Utku; Yozgat, Can Yilmaz; Karadeniz, Cem; ERGÖR, Serap Nur; ERENBERK, UFUK; YOZGAT, YILMAZ; OTÇU TEMUR, HAFİZE; ERGÖR, SERAP NUR; ERENBERK, UFUKBackground: To evaluate the short-term effectiveness of reduced-osmolarity oral rehydration salt formulation (ORS) and propranolol in children diagnosed with postural orthostatic tachycardia syndrome (POTS) in head-up tilt testing (HUTT).