2014-01-01, Yılmaz, Enver Demirel, Deveci, ERDEM, Kadıoğlu, HÜSEYİN, Gençe, Ali Görkem, Ünal, Özge, Koçer, Emel, KIRPINAR, İSMET, DEVECİ, ERDEM, KADIOĞLU, HÜSEYİN, KIRPINAR, İSMET

2019-01-01, ÖZTÜRK, AHMET, Şahan, Ebru, MIRÇIK, ALİ BARLAS, DEVECİ, ERDEM, YILMAZ, ONUR, KIRPINAR, İSMET, ÖZTÜRK, AHMET, ŞAHAN, EBRU, MIRÇIK, ALİ BARLAS, DEVECİ, ERDEM, YILMAZ, ONUR, KIRPINAR, İSMET

Objective: Not only white blood cells but also platelets are being considered in inflammatory reactions from now on. Mean platelet volume (MPV) and neutrophil to lymphocyte ratio (NLR) have been shown to change in inflammatory diseases like myocardial infarction, stroke and implicated in psychiatric disorders nowadays. Our first aim is to investigate the relation of MPV and NLR with depression and secondly to assess if they change with the treatment of depression. Methods: Forty-nine patients diagnosed with major depressive disorder (MDD) and hospitalized in a university hospital psychiatry inpatient unit retrospectively included in the study. Control group consisted of 48 hospital workers with no known disease. Complete blood count, Hamilton Depression Rating Scale (HAM-D) and Clinical Global Impression-Severity Scale (CGI-S) scores at admission and at discharge were noted and compared for the patient group. Discussion: MPV of depressed patients was higher than controls. When we look at admission and discharge scores of clinical scales, decrement is statistically significant for both HAM-D and CGI-S. There was decline both in MPV and NLR which were both statistically significant. Conclusion: Decreasing MPV and NLR values with the treatment of depression confirm the involvement of inflammatory processes in the pathophysiology of depression.

2014-11-01, DEVECİ, ERDEM, ÖZTÜRK, AHMET, KIRPINAR, İSMET, KOYUNCU, AHMET, ENGİN, İSMAİL, MELİKOĞLU, MEHMET, YILMAZ, ENVER DEMİREL, KOÇER, EMEL, DEVECİ, ERDEM, ÖZTÜRK, AHMET, KIRPINAR, İSMET

2014-12-01T00:00:00Z, Bagcioglu, Erman, Bahceci, Bulent, Deveci, Erdem, Ozturk, AHMET, Sasmaz, Sezai, Karaaslan, Mehmet Fatih, ÖZTÜRK, AHMET, DEVECİ, ERDEM

Background and Design: In this study, we evaluated anxiety and depression levels, levels of problem solving, focus of control, tendency to anger and quality of life in patients with acne as well as the association between those parameters and the clinical features of acne. Materials and Methods: Fifty-two patients with mild to severe acne vulgaris and 46 healthy controls were enrolled. Acne severity was graded in all patients by a dermatologist. The Montgomery-Asberg Depression Rating Scale (MADRS), Hamilton Anxiety Rating Scale (HAM-A), Brief Symptom Inventory (BSI), Problem Solving Inventory (PSI), The State-Trait Anger Scale (STAS), Rotter's Internal-External Focus of Control Scale (RIELCS) and the Short Form 36-Item Health Survey (SF-36) were applied to all participants. Results: In our study, we found out that anxiety and depression scores were significantly higher in patients with acne vulgaris than in controls. In BSI, anxiety disorders, depression, interpersonal sensitivity, and paranoid thoughts scores were significantly higher in patients with acne than in controls. According to SF-36, physical role difficulty, general health and mental health scores were significantly lower in patients with acne. Conclusion: The results of our study support the previous findings suggesting that acne vulgaris leads to various psychiatric problems, such as depression and anxiety and, adversely affects quality of life of patients.

2020-05-01T00:00:00Z, Yılmaz, Onur, Kılıçarslan, Tezer, Kevser Boyraz, Rabia, Parlakkaya, Fatma Büşra, Deveci, Erdem, Öztürk, Ahmet, PARLAKKAYA, FATMA BÜŞRA, DEVECİ, ERDEM

2021-09-01T00:00:00Z, Kolemen, Ayse B., Akyuz, Enes, TOPRAK, ALİ, Deveci, Erdem, YEŞİL SAYIN, Gözde, AKYÜZ, ENES, TOPRAK, ALİ, DEVECİ, ERDEM

Background: The diagnosis of the rare genetic diseases has great importance in treating multisystemic conditions, preventing potential complications, and estimating disease risk for family members. The duration of obtaining genetic test results is varies. The demand to learn the diagnosis of a possible untreatable illness involves a struggle between uncertainty and a lifetime chronic disease. The current uncertainty of their child's condition and the long wait for a diagnosis may increase the parents' anxiety level and cause difficulties in the continuation of diagnostic procedures in some families. This study aimed to investigate the prediagnosis and postdiagnosis anxiety levels of parents who have a child with a rare genetic disease. Method: The parents in this study, mothers or fathers, admitted their children to the Bezmialem Vakıf University Medical Genetics Clinic due to a suspected rare genetic disease (n = 40). Researchers created "The Sociodemographic Questionnaire" and used it to analyze the parents' sociodemographic status. In addition, they used the State-Trait Anxiety Inventory (STAI) to determine the anxiety levels of the parents. Results: The state anxiety levels of parents decreased significantly after learning the diagnosis. However, there was no statistically significant decrease observed in trait anxiety levels. Conclusion: Data from this study revealed that informing parents about their child's disease and properly explaining to them the expected difficulties might help to reduce their anxiety levels. Psychological support for parents is necessary to reduce their long-term stress, thus increasing the patient's compliance with treatment.

2019-01-01, DEVECİ, ERDEM, Kocacenk, Tuba, ŞAHAN, EBRU, YILMAZ, ONUR, ÖZTÜRK, AHMET, KIRPINAR, İSMET, DEVECİ, ERDEM, ŞAHAN, EBRU, YILMAZ, ONUR, ÖZTÜRK, AHMET, KIRPINAR, İSMET

2014-09-01, Ozturk, AHMET, Deveci, ERDEM, DURSUN, Ali Emre, Soyucok, Etem, Kirpinar, Ismet, DEVECİ, ERDEM, KIRPINAR, İSMET

2014-04-01, KIRPINAR, İSMET, DEVECİ, ERDEM, ZİHNİ, DEMET, KILIÇ, ALPEREN, KIRPINAR, İSMET, DEVECİ, ERDEM

2018-04-01, KILIÇ, Alperen, Ozturk, AHMET, Deveci, ERDEM, Kirpinar, Ismet, ÖZTÜRK, AHMET, DEVECİ, ERDEM, KIRPINAR, İSMET

Hyperprolactinemia is characterized by abnormally increased serum prolactin levels. Menstrual irregularities and hyperprolactinemia can be caused by a variety of medical conditions as well as due to the use of some psychopharmacological drugs, namely antipsychotics; it can also develop during antidepressant treatment. Bupropion is an antidepressant functioning via the inhibition of noradrenaline and dopamine reuptake. The endocrine and sexual adverse events of this agent are rare. In the literature, only one case reporting hyperprolactinemia or galactorrhea caused by bupropion use is available. Here, we present the case of a patient diagnosed with depressive disorder and receiving venlafaxine, who developed hyperprolactinemia and oligomenorrhea after the addition of bupropion the ongoing treatment and showed serum prolactin levels decreased to normal ranges shortly after the discontinuation of bupropion.