2020-06-01T00:00:00Z, GÖKMEN KARASU, AYŞE FİLİZ, AYDIN, SERDAR, ATEŞ, SEDA, TAKMAZ, TAHA, Comba, Cihan, GÖKMEN KARASU, AYŞE FİLİZ, AYDIN, SERDAR, ATEŞ, SEDA, TAKMAZ, TAHA

Introduction:Our objective was to compare the effect of rectal misoprostol (Cytotec) versus rectal hyoscine-n-butyl bromide (Buscopan) on patients undergoing hysteroscopy. We hypothesised that HBB may have a role in cervical priming. Material and methods:This trial was conducted at Bezmialem Vakif University Hospital. Women of reproductive age between 18-50 years who were scheduled for operative hysteroscopy indicated by type 1 submucous myoma or endometrial polyps were recruited for the study. Ninety patients were divided randomly into three groups. Group 1 received placebo treatment. Group 2 received rectal 200 mcg misoprostol and Group 3 received rectal 20 mg hyoscine-n-butyl bromide two hours before the procedure. Procedures were performed using a bipolar 26 F (9 mm) continuous-flow rigid resectoscope with a 30 degrees lens. The outcome measures included cervical dilation width and time, ease of cervical dilation, procedure time and operative complications. Postoperative self-rated pain was assessed one hour after the procedure. Results:Thirteen patients (43. 3%) in the placebo treatment group, 11 patients (36.7%) in the misoprostol group and four patients (13.3%) in the hyoscine-n-butyl bromide group needed analgesics postoperatively (p = .02). The mean duration of cervical dilation time was longest in Group 1 and shortest in Group 3, however this difference did not reach statistical significance (p=.11). There was no difference with regard to other studied parameters. Summary:HBB reduced the need for pain medication compared to placebo. Larger studies are needed to further investigate the role of HBB in facilitating pre-operative cervical priming.

2020-01-01T00:00:00Z, ATEŞ, SEDA, Karasu, Ayse Filiz Gokmen, ÇALI, HALİME, Soyman, Zeynep, UYSAL, ÖMER, ATEŞ, SEDA, ÇALI, HALİME, UYSAL, ÖMER

Aim: To assess the risk factors associated with high rate of insufficient endometrial sampling on endometrial biopsy in postmenopausal women.

2022-05-28, Çetin Ç., Dural H. R., Ateş S., Tanoğlu F. B., Kütük M. S., Özcan P., ÇETİN, ÇAĞLAR, ATEŞ, SEDA, KÜTÜK, MEHMET SERDAR, ÖZCAN, PINAR

2020-12-07T00:00:00Z, Gökmen Karasu, Ayşe Filiz, Aydın, Serdar, Ateş, SEDA, Arıoğlu, Çağrı, ATEŞ, SEDA, GÖKMEN KARASU, AYŞE FİLİZ

2020-01-01T00:00:00Z, ATEŞ, SEDA, GÖKMEN KARASU, AYŞE FİLİZ, ÇALI, HALİME, SOYMAN, ZEYNEP, UYSAL, ÖMER, ATEŞ, SEDA, GÖKMEN KARASU, AYŞE FİLİZ, ÇALI, HALİME, UYSAL, ÖMER

2022-07-01T00:00:00Z, ATEŞ, SEDA, Aydin, Serdar, ÖZCAN, PINAR, ATEŞ, SEDA, ÖZCAN, PINAR

The aim of this study was to investigate the reproductive profiles, metabolic parameters and cardiometabolic risk assessed by surrogate indexes in women with adenomyosis. Ninety-six premenopausal women who were diagnosed with adenomyosis by transvaginal ultrasound and 97 age-body mass index (BMI) matched controls with normal ultrasound during routine examination were included. Women with adenomyosis were more likely to have higher gravidity and had more abortions than women without adenomyosis. Regarding the individual metabolic syndrome components, the adenomyosis group was more likely to have higher prevalence of hypertension, low HDL-C and central obesity. No significant difference was found between the groups in terms of visceral adiposity index, lipid accumulation product and fatty liver index. Only higher blood pressure (BP) remained statistically significant after adjustment for confounding factors in multivariate analysis. Women with adenomyosis had remarkably high risk of hypertension. It may be advisable to monitor their BP closely.Impact Statement What is already known on this subject? The only anthropometric characteristic assessed in women in relation to adenomyosis is body mass index (BMI). A case-control study showed that women who are obese are more likely to have adenomyosis. The gravidity, number of spontaneous abortions and previous uterine surgeries such as dilatation and curettage (D&C) and caesarean section were found significantly associated with adenomyosis. What do the results of this study add? A remarkable finding of our study was the increased incidence of higher systolic BP in women with adenomyosis. No difference was observed in adiposity indices between women with and without adenomyosis. Higher prevalence of central obesity and lower HDL-C levels were seen in women with adenomyosis. What are the implications of these findings for clinical practice and/or further research? The study identifies that adenomyosis is associated with an increased risk of hypertension, and women with adenomyosis may be monitored closely for blood pressure changes. Our report also provides novel information about the metabolic risk profiles associated with adenomyosis.

2022-05-01T00:00:00Z, ATEŞ, SEDA, Aydin, Serdar, ÖZCAN, PINAR, BAKAR, Rabia Zehra, ÇETİN, ÇAĞLAR, ATEŞ, SEDA, ÖZCAN, PINAR, BAKAR, RABIA ZEHRA, ÇETİN, ÇAĞLAR

Purpose To assess sleep disturbances, levels of anxiety, depression and fatigue in women with premature ovarian insufficiency (POI). Materials and methods The study included 62 women with POI and 62 age-matched controls. Women in both groups completed questionnaires. Pittsburgh Sleep Quality Index, Insomnia severity index, Epworth Sleepiness Scale, Hospital Anxiety and Depression Scale and Fatigue Severity Scale were used. Results We found poor sleep quality, higher levels of insomnia in women with POI than in controls. Depression was much more prevalent and severe in POI women. Total anxiety score, the severity of anxiety and fatigue did not differ significantly between the groups. According to the multivariable logistic regression analysis, being married and having POI were associated with worse quality of sleep, and having more children was associated with an increase in depression levels in the whole cohort. Backward analysis showed that when POI status was taken as a reference, married women were at 6.5 fold increased risk of poor sleep quality. Conclusions Women with premature ovarian failure are more likely to suffer from poor sleep quality, insomnia and depression than healthy women.