Goal:
17 - Amaçlar için Ortaklıklar

Project Logo
Description
Amaçlar için Ortaklıklar Uygulama araçlarını güçlendirmek ve sürdürülebilir kalkınma için küresel ortaklığı canlandırmak. Hedefler, tüm hedefleri başarmak üzere ulusal planları desteklemek suretiyle Kuzey-Güney ve Güney-Güney işbirliğini artırma amacını güdüyor. Uluslararası ticaretin geliştirilmesi ve gelişmekte olan ülkelerin ihracatını artırmalarına destek verilmesi, adil ve açık, herkesin yararına olan, evrensel kurallara dayalı ve hakkaniyetli bir ticaret sistemini oluşturmanın unsurlarıdır.

Filters

2010 - 2019112020 - 202210
Reset filters

Settings

Type: Article ×

Publication Search Results

Now showing 1 - 10 of 21
  • No Thumbnail Available
    PublicationMetadata only
    Palliative Care in High and Low Resource Countries
    (2021-01-01T00:00:00Z) KEBUDİ, Rejin; ÇAKIR, FATMA BETÜL; Silbermann, Michael; ÇAKIR, FATMA BETÜL
    Palliative Care (PC) is defined by the World Health Organization (WHO) as a support provided by multiple disciplines in order to improve the quality of life of both patients and their caregivers, throughout the disease course, from diagnosis to end- of-life. PC aims to prevent and treat symptoms and side effects of the disease and its treatment. PC is well developed in most high-income countries; however in most low-income settings, where approximately 80% of patients with cancer requiring PC care for advanced disease live, PC services are still uncommon. Health indicators monitoring global PC development are policy, education, use of medicines, service provision and professional activity. Globally, PC development may be categorized as Group 1 (no known hospice-PC activity), Group 2 (capacity-building activity), Groups 3a Isolated PC provided, 3b Generalized PC provided, 4a hospice-PC services at a stage of integration into regular service provision, and 4b hospice-PC services at a stage of advanced integration into regular service provision. Spirituality is an essential element of patient-centered PC. The use of Complementary and Traditional Medicine (CTM) in Middle Eastern countries is widespread. There are wide discrepancies in cancer care and PC in many regions of the world. The Individualized Care Planning and Coordination (ICPC) Model is designed to facilitate the advance care planning with continuity of all the measures like symptom control or emotional, social and spiritual care of both the patient and the family during the disease steps like relapse or end of life.
  • Thumbnail Image
    PublicationOpen Access
    Acute kidney injury in Turkey: epidemiological characteristics, etiology, clinical course, and prognosis
    (2022-10-01T00:00:00Z) GÜRSU, Meltem; Yegenaga, Itir; TUĞLULAR, ZÜBEYDE SERHAN; DURSUN, BELDA; GÖKÇAY BEK, SİBEL; Bardak, Simge; ONAN, ENGİN; Demir, Serap; DERİCİ, ÜLVER; DOĞUKAN, AYHAN; Sevinc, Mustafa; KOÇYİĞİT, İSMAİL; Altun, Eda; Haras, Ali Burak; ALTIPARMAK, Mehmet Rıza; TONBUL, HALİL ZEKİ; GÜRSU, MELTEM
    Background: This study aimed to evaluate the etiologies, comorbidities, and outcomes of acute kidney injury (AKI) in Turkey and determine any potential differences among different geographical parts of the country. Methods: This prospective observational study was conducted by the Acute Kidney Injury Working Group of the Turkish Society of Nephrology. Demographical and clinical data of patients with AKI at the time of diagnosis and at the 1st week and 1st, 3rd, and 6th months of diagnosis were evaluated to determine patient and renal survival and factors associated with patient prognosis. Results: A total of 776 patients were included (54.7% male, median age: 67 years). Prerenal etiologies, including dehydration, heart failure, and sepsis, were more frequent than other etiologies. 58.9% of the patients had at least one renal etiology, with nephrotoxic agent exposure as the most common etiology. The etiologic factors were mostly similar throughout the country. 33.6% of the patients needed kidney replacement therapy. At the 6th month of diagnosis, 29.5% of the patients had complete recovery; 34.1% had partial recovery; 9.5% developed end-stage kidney disease; and 24.1% died. The mortality rate was higher in the patients from the Eastern Anatolian region; those admitted to the intensive care unit; those with prerenal, renal, and postrenal etiologies together, stage 3 AKI, sepsis, cirrhosis, heart failure, and malignancy; those who need kidney replacement therapy; and those without chronic kidney disease than in the other patients. Conclusion: Physicians managing patients with AKI should be alert against dehydration, heart failure, sepsis, and nephrotoxic agent exposure. Understanding the characteristics and outcomes of patients with AKI in their countries would help prevent AKI and improve treatment strategies.
  • Thumbnail Image
    PublicationOpen Access
    Gene Hunting Approaches through the Combination of Linkage Analysis with Whole-Exome Sequencing in Mendelian Diseases: From Darwin to the Present Day
    (2021-07-08T00:00:00Z) Susgun, Seda; Kasan, Koray; Yucesan, Emrah; SÜSGÜN, SEDA; YÜCESAN, EMRAH
    Background: In the context of medical genetics, gene hunting is the process of identifying and functionally characterizing genes or genetic variations that contribute to disease phenotypes. In this review, we would like to summarize gene hunting process in terms of historical aspects from Darwin to now. For this purpose, different approaches and recent developments will be detailed. Summary: Linkage analysis and association studies are the most common methods in use for explaining the genetic background of hereditary diseases and disorders. Although linkage analysis is a relatively old approach, it is still a powerful method to detect disease-causing rare variants using family-based data, particularly for consanguineous marriages. As is known that, consanguineous marriages or endogamy poses a social problem in developing countries, however, this same condition also provides a unique opportunity for scientists to identify and characterize pathogenic variants. The rapid advancements in sequencing technologies and their parallel implementation together with linkage analyses now allow us to identify the candidate variants related to diseases in a relatively short time. Furthermore, we can now go one step further and functionally characterize the causative variant through in vitro and in vivo studies and unveil the variant-phenotype relationships on a molecular level more robustly. Key Messages: Herein, we suggest that the combined analysis of linkage and exome analysis is a powerful and precise tool to diagnose clinically rare and recessively inherited conditions.
  • Thumbnail Image
    PublicationOpen Access
    Global capacity for clinical research in nephrology: a survey by the International Society of Nephrology
    (2018-02-01) Okpechi, Ikechi G.; Alrukhaimi, Mona; Ashuntantang, Gloria E.; Bellorin-Font, Ezequiel; Gharbi, Mohammed Benghanem; Braam, Branko; Feehally, John; Harris, David C.; Jha, Vivekanand; Jindal, Kailash; Johnson, David W.; Kalantar-Zadeh, Kamyar; Kazancioglu, RÜMEYZA; Levin, Adeera; Lunney, Meaghan; Olanrewaju, Timothy Olusegun; Perkovic, Vlado; Perl, Jeffrey; Rashid, Harun Ur; Rondeau, Eric; Salako, Babatunde lawal; Samimi, Arian; Sola, Laura; Tchokhonelidze, Irma; Wiebe, Natasha; Yang, Chih-Wei; Ye, Feng; Zemchenkov, Alexander; Zhao, Ming-hui; Bello, Aminu K.; KAZANCIOĞLU, RÜMEYZA
    Due to the worldwide rising prevalence of chronic kidney disease (CKD), there is a need to develop strategies through well-designed clinical studies to guide decision making and improve delivery of care to CKD patients. A cross-sectional survey was conducted based on the International Society of Nephrology Global Kidney Health Atlas data. For this study, the survey assessed the capacity of various countries and world regions in participating in and conducting kidney research. Availability of national funding for clinical trials was low (27%, n = 31), with the lowest figures obtained from Africa (7%, n = 2) and South Asia (0%), whereas high-income countries in North America and Europe had the highest participation in clinical trials. Overall, formal training to conduct clinical trials was inadequate for physicians (46%, n = 53) and even lower for nonphysicians, research assistants, and associates in clinical trials (34%, n = 39). There was also diminished availability of workforce and funding to conduct observational cohort studies in nephrology, and participation in highly specialized transplant trials was low in many regions. Overall, the availability of infrastructure (bio-banking and facilities for storage of clinical trial medications) was low, and it was lowest in low-income and lower-middle-income countries. Ethics approval for study conduct was mandatory in 91% (n = 106) of countries and regions, and 62% (n = 66) were reported to have institutional committees. Challenges with obtaining timely approval for a study were reported in 53% (n = 61) of regions but the challenges were similar across these regions. A potential limitation is the possibility of over-reporting or under-reporting due to social desirability bias. This study highlights some of the major challenges for participating in and conducting kidney research and offers suggestions for improving global kidney research.
  • No Thumbnail Available
    PublicationMetadata only
    IFLA President-s Meeting 2015 Istanbul
    (2015-01-01T00:00:00Z) Zayim, KÜBRA; ZAYİM GEDİK, KÜBRA
    International Federation of Library Associations and Institutions (IFLA) organizing presidency meetings in connection with the developments for library and information services by the themes defined. Eighth Meeting of Presidency has been organized in cooperation with ANKOS, Turkish Librarians- Association (TLA), Istanbul BilgiUniversity in Istanbul with the invited speakers and attendants from various disciplines. The meeting titled in -The Art of Transformation of Libraries- was carried out in the framework organized under the five major themes. These titles are:
  • No Thumbnail Available
    PublicationMetadata only
    The Disease that is Unforgettable: a Case of Rapidly Progressive Tetanus
    (2013-09-01T00:00:00Z) Koruk, Suda Tekin; Sogut, Ozgur; Karaagac, Leman; Calisir, Celal; Yalcin, Saban
    Tetanus is an acutely progressive central nervous system (CNS) infection characterized by severe respiratory distress and persistent tonic spasms. The bacteria toxin which is largely responsible for the clinical course of tetanus is tetanospasmin, which is effective in the central and autonomous nerve system and the neuromuscular junction. The symptoms arise with the toxin reaching the CNS generally within 10-14 days. Shortness of incubation period is a negative prognostic factor. Its prevalence in developed countries has been reduced with primary and secondary immunization programs made in each decade. However, it is still a serious public health issue in developing countries. In this paper, the aim was to present a case of fatal tetanus, who had received his last immunoprophylaxis about 25 years ago and had a rapidly progressive clinical course.
  • No Thumbnail Available
    PublicationMetadata only
    Impact of maternal anxiety level on the childhood vaccination coverage.
    (2010-11-01) ÖZKAYA, EMİN; ÖZKAYA, EMİN
    The mother-s mental state as a risk factor for the children-s vaccination status in developing countries has received little attention. The aim of this study was to determine the association between childhood vaccination coverage and maternal anxiety. A total of 195 consecutive infants and their mothers attending a tertiary teaching hospital, department of pediatric outpatient center between January 2008 and September 2009 were included in the study. One hundred five infants who have incomplete vaccination schedule (according to the National Immunization Schedule) were matched with 90 controls (fully vaccinated) and their mothers self-report measure of anxiety level using the State-Trait Anxiety Inventory (STAI), a psychiatric screening instrument. The chi-square test and the logistic regression were used in the statistical analysis. High maternal anxiety levels determined by STAI was associated with increased risk of incomplete vaccination status in infants (odds ratio 4.35, 95% confidence interval 1.87-8.79).This association remained significant after controlling for sociodemographic factors. High maternal anxiety scores may result in incomplete vaccination status in children younger than 3 years.
  • Thumbnail Image
    PublicationOpen Access
    Global nephrology workforce: gaps and opportunities toward a sustainable kidney care system
    (2018-02-01) Osman, Mohamed A.; Alrukhaimi, Mona; Ashuntantang, Gloria E.; Bellorin-Font, Ezequiel; Gharbi, Mohammed Benghanem; Braam, Branko; Courtney, Mark; Feehally, John; Harris, David C.; Jha, Vivekanand; Jindal, Kailash; Johnson, David W.; Kalantar-Zadeh, Kamyar; Kazancioglu, RÜMEYZA; Klarenbach, Scott; Levin, Adeera; Lunney, Meaghan; Okpechi, Ikechi G.; Olanrewaju, Timothy Olusegun; Perl, Jeffrey; Rashid, Harun Ur; Rondeau, Eric; Salako, Babatunde lawal; Samimi, Arian; Sola, Laura; Tchokhonelidze, Irma; Wiebe, Natasha; Yang, Chih-Wei; Ye, Feng; Zemchenkov, Alexander; Zhao, Ming-hui; Bello, Aminu K.; KAZANCIOĞLU, RÜMEYZA
    The health workforce is the cornerstone of any health care system. An adequately trained and sufficiently staffed workforce is essential to reach universal health coverage. In particular, a nephrology workforce is critical to meet the growing worldwide burden of kidney disease. Despite some attempts, the global nephrology workforce and training capacity remains widely unknown. This multinational cross-sectional survey was part of the Global Kidney Health Atlas project, a new initiative administered by the International Society of Nephrology (ISN). The objective of this study was to address the existing global nephrology workforce and training capacity. The questionnaire was administered online, and all data were analyzed and presented by ISN regions and World Bank country classification. Overall, 125 United Nations member states responded to the entire survey, with 121 countries responding to survey questions pertaining to the nephrology workforce. The global nephrologist density was 8.83 per million population (PMP); high-income countries reported a nephrologist density of 28.52 PMP compared with 0.31 PMP in low-income countries. Similarly, the global nephrologist trainee density was 1.87 PMP; high-income countries reported a 30 times greater nephrology trainee density than low-income countries (6.03 PMP vs. 0.18 PMP). Countries reported a shortage in all care providers in nephrology. A nephrology training program existed in 79% of countries, ranging from 97% in high-income countries to 41% in low-income countries. In countries with a training program, the majority (86%) of programs were 2 to 4 years, and the most common training structure (56%) was following general internal medicine. We found significant variation in the global density of nephrologists and nephrology trainees and shortages in all care providers in nephrology; the gap was more prominent in low-income countries, particularly in African and South Asian ISN regions. These findings point to significant gaps in the current nephrology workforce and opportunities for countries and regions to develop and maintain a sustainable workforce.
  • No Thumbnail Available
    PublicationMetadata only
    Incidence and outcomes of eclampsia: a single-center 30-year study
    (2019-04-01T00:00:00Z) Uludag, Semih Zeki; Karasu, AYŞE FİLİZ; KÜTÜK, MEHMET SERDAR; TAKMAZ, TAHA; GÖKMEN KARASU, AYŞE FİLİZ; KÜTÜK, MEHMET SERDAR; TAKMAZ, TAHA
    Objective: We aimed to determine the incidence of eclampsia at Erciyes University Hospital which is a tertiary referral center situated at central Anatolia. Additionally, we investigated eclampsia-associated maternal and perinatal outcomes for the 30-year study period. Methods: A retrospective review was performed for all women who were diagnosed with eclampsia and admitted to the Erciyes University Medical School, Department of Obstetrics and Gynecology from January 1985 to December 2015. Improvement in management gained over time was determined by comparing the results of the years 2005-2015 with data which were already published from years 1985-1999 and 2000-2004. Results: Eclampsia prevalence was 289/46,928 (% 0.61). Maternal age at the time of diagnosis did not differ statistically; however, gestational age at diagnosis and birth weight decreased significantly throughout the years (p < 0.005). The perinatal mortality rate showed a slight decrease throughout the years (p = 0.238). Maternal mortality rate also decreased throughout the years; it was 1.7% in 2005-2009 and 0 % in 2010-2015 (p = 0.246). Conclusion: The prevalence of eclampsia cases has decreased over the years. Maternal mortality attributed to eclampsia has also declined. The early diagnosis and treatment of eclampsia have resulted in the increase of premature deliveries. The perinatal mortality rate showed a slight decrease throughout the years (p = 0.238); however, it is not at a desirable rate compared to developed countries.
  • No Thumbnail Available
    PublicationMetadata only
    A novel id-iri score: development and internal validation of the multivariable community acquired sepsis clinical risk prediction model
    (2020-04-01T00:00:00Z) Diktas, Husrev; Uysal, Serhat; Erdem, Hakan; Cag, Yasemin; Miftode, Egidia; Durmus, Gul; ULU KILIÇ, AYŞEGÜL; Alabay, Selma; Szabo, Balint Gergely; Lakatos, Botond; Fernandez, Ricardo; Korkmaz, Pinar; Caliz, Michael Cruz; Argemi, Xavier; Kulzhanova, Sholpan; Kormaz, Fatime; Yilmaz-Karadag, Fatma; Ergen, Pinar; Atilla, Aynur; Puca, Edmond; Dogan, Mustafa; Mangani, Francesca; Sahin, Suzan; Grgic, Svjetlana; Grozdanovski, Krsto; Yilmaz, Gul Ruhsar; Del-Vecchio, Rosa Fontana; Demirel, Aslihan; SIRMATEL, FATMA; ŞENER, ALPER; Sacar, Suzan; Aydin, Emsal; Batirel, Ayse; Dragovac, Gorana; El-Sokkary, Rehab; Alexandru, Crisan; Arslan-Ozel, Selcan; BOLUKÇU, SİBEL; Ozkaya, H. Deniz; Nayman-Alpat, Saygin; Inan, Asuman; Al-majid, Fahad; Kaya-Ugur, Berna; Rello, Jordi; BOLUKÇU, SİBEL
    We aimed to develop a scoring system for predicting in-hospital mortality of community-acquired (CA) sepsis patients. This was a prospective, observational multicenter study performed to analyze CA sepsis among adult patients through ID-IRI (Infectious Diseases International Research Initiative) at 32 centers in 10 countries between December 1, 2015, and May 15, 2016. After baseline evaluation, we used univariate analysis at the second and logistic regression analysis at the third phase. In this prospective observational study, data of 373 cases with CA sepsis or septic shock were submitted from 32 referral centers in 10 countries. The median age was 68 (51-77) years, and 174 (46,6%) of the patients were females. The median hospitalization time of the patients was 15 (10-21) days. Overall mortality rate due to CA sepsis was 17.7% (n = 66). The possible predictors which have strong correlation and the variables that cause collinearity are acute oliguria, altered consciousness, persistent hypotension, fever, serum creatinine, age, and serum total protein. CAS (%) is a new scoring system and works in accordance with the parameters in third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). The system has yielded successful results in terms of predicting mortality in CA sepsis patients.