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16 - Barış, Adalet ve Güçlü Kurumlar

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Barış, Adalet ve Güçlü Kurumlar Sürdürülebilir kalkınma için barışçıl ve kapsayıcı toplumlar tesis etmek, herkes için adalete erişimi sağlamak ve her düzeyde etkili, hesap verebilir ve kapsayıcı kurumlar oluşturmak. Barış, istikrar, insan hakları ve hukukun üstünlüğüne dayalı etkin yönetim olmadan, sürdürülebilir kalkınma olmasını bekleyemeyiz. Gittikçe artan ölçüde bölünmüş bir dünyada yaşıyoruz. Bazı bölgelerde barış, güvenlik ve refah sürekli iken, diğer bazı bölgelerde ise bitmek bilmeyen çatışma ve şiddet sarmalı var. Ancak bu, hiçbir şekilde kaçınılmaz sonuç değildir ve mutlaka çözümlenmelidir.

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PublicationOpen Access

Discordance between Serum Neutralizing Antibody Titers and the Recovery from COVID-19

2020-09-25T00:00:00Z, Koç, Mm, Kalkan, Yazıcı, Çetin, Nesibe Selma, Doymaz, Mz, Sümbül, B, Durdu, B, YAZICI, MERVE, MERİÇ KOÇ, MELİHA, ÇETİN, NESİBE SELMA, KARAASLAN, ELİF, OKAY, GÜLAY, DURDU, BÜLENT, SÜMBÜL, BİLGE, DOYMAZ, MEHMET ZIYA

The recent pandemic of COVID-19 has caused a tremendous alarm around the world. Details of the infection process in the host have significant bearings on both recovery from the disease and on the correlates of the protection from the future exposures. One of these factors is the presence and titers of neutralizing Abs (NAbs) in infected people. In the current study, we set out to investigate NAbs in the recovered subjects discharged from the hospital in full health. Serum samples from a total of 49 documented consecutive COVID-19 subjects were included in the study. All the subjects were adults, and serum samples collected during the discharge were tested in viral neutralization, enzyme immunoassay (EIA), and Western immunoblot tests against viral Ags. Even though a majority of the recovered subjects had raised significant NAb titers, there is a substantial number of recovered patients (10 out of 49) with no or low titers of NAbs against the virus. In these cohorts as well as in patients with high NAb titers, viral Ag binding Abs were detectable in EIA tests. Both NAb titers and EIA detectable Abs are increased in patients experiencing a severe form of the disease, and in older patients the Ab titers were heightened. The main conclusion is that the recovery from SARS-CoV-2 infection is not solely dependent on high NAb titers in affected subjects, and this recovery process is probably produced by a complex interplay between many factors, including immune response, age of the subjects, and viral pathology.

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PublicationOpen Access

Perioperative Precautions for Novel Coronavirus Outbreak

2020-11-01T00:00:00Z, Dağcı, Mahmut, Alptekin, Hatice Merve, DAĞCI, MAHMUT

Coronavirus disease 2019 (COVID-19) virus, a sub-member of the coronavirus family, that first appeared in China, has been declared a pandemic in the world due to its rapid spread and spread by airborne transmission. Since all patients diagnosed with COVID-19 do not have symptoms, it is difficult to recognize people with or without disease. When patients with suspected or diagnosed COVID-19 surgery need to be operated in urgent or emergent situations, measures must be taken to protect the patient and the operating room staff. The operating room team should know the procedures to be applied if fixtures and surgical instruments in the operating room are used in cases of suspected COVID-19. In these cases, training should be provided on the effective use of personal protective equipment, precautions to be taken, and health institutions should be able to manage the preoperative, perioperative and postoperative process of patients with suspected COVID-19 or diagnosis. Health institutions should prepare an emergency plan to be applied in pandemic situations. The aim of this was study to present how to manage the perioperative process of surgical patients in COVID-19 pandemic.

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PublicationOpen Access

COVID-19 and Phytotherapy

2020-10-01T00:00:00Z, Akbaş, Melike Nur, Akçakaya, Adem, AKBAŞ, MELİKE NUR, AKÇAKAYA, ADEM

SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), emerging in Wuhan city, China, causing COVID-19 disease, has been described as a pandemic by WHO (World Health Organization), leading to outbreaks of pneumonia. The COVID-19 pandemic continues to affect millions of people worldwide. SARS-COV-2 enters the cell via ACE-2 (Angiotensin-converting enzyme 2) receptor. These receptors are predominantly found in lung, small intestine, and vascular endothelial cells. Since ACE 2 is found more frequently in these tissues, common clinical symptoms include fever, cough, sore throat, fatigue, dyspnea, and diarrhea. Currently, although symptomatic treatments are applied for COVID-19, there is no specific treatment yet. It takes a long time before targeted therapies can be found. For this reason, it is necessary to develop emergency treatment or methods that can quickly control the disease. Phytotherapeutic compositions offer a potentially valuable resource for this purpose. Many countries, especially China, aimed to reduce morbidity and mortality by using phytotherapy throughout COVID-19 patients. Phytotherapeutic products are known to be safe and tolerable with their background knowledge. In this regard, the use of phytotherapy as a complementary treatment in COVID-19 patients is very important. In this review, phytotherapeutic approaches related to symptoms that may occur in the clinical course of COVID-19 disease will be discussed.

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PublicationOpen Access

Recommendations for management of diabetic foot ulcers during COVID-19 outbreak.

2020-06-05T00:00:00Z, Kelahmetoglu, Osman, Camlı, Mf, Kirazoglu, A, Erbayat, Y, Guneren, E, Asgarzade, S, Durgun, U, Mehdizade, T, Yeniocak, A, Yildiz, K, Sonmez, Ergun, KELAHMETOĞLU, OSMAN, ERGÜN, SELMA, GÜNEREN, ETHEM

COVID-19 pandemia began in Wuhan, China, in December 2019. A total of 1 878 489 people were infected and 119 044 people were lost because of the disease and its complications by 15 April. Severe morbidity and mortality complications are mostly seen in elderly and patients having comorbidities. Diabetic foot ulcers (DFUs) are one of severe complications of diabetes mellitus and it may require urgent surgical interventions. In this paper, we aimed to create a management algorithm to prevent the unexpected complications that may occur in the patients and health care workers during the evaluation of COVID-19 in DFU patients who require urgent surgical intervention. We advise the use of thorax computerised tomography for preoperative screening in all DFU patients with severe signs of infection and especially those requiring urgent surgery for both the detection of the possible undiagnosed COVID-19 in the patient for the need for close follow-up and protection of the surgical and anaesthesiology team.

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PublicationOpen Access

What Has Changed in the Treatment of Psoriatic Arthritis After COVID-19?

2021-06-01T00:00:00Z, KESKİN, Yaşar, Koz, Gokhan, Nas, Kemal, KESKİN, YAŞAR

Coronavirus disease 2019 is a respiratory infection caused by severe acute respiratory syndrome coronavirus 2. Coronavirus disease 2019 leads to the rapid activation of innate immune cells, particularly in patients with severe disease. Psoriatic arthritis is a heterogeneous chronic inflammatory disease characterized by the association of psoriasis and arthritis. Similar to those with other viruses, patients with psoriatic arthritis are at a significant risk of infection with severe acute respiratory syndrome coronavirus 2. Patients with psoriatic arthritis are immunosuppressed owing to immune dysregulation during the active disease period or owing to immunosuppressive drugs administered during remission, and they are prone to infections. The severe acute respiratory syndrome coronavirus 2 is a threat to millions of people globally owing to the decline in immunity and because a significant number of people develop severe illness. In the period of coronavirus disease 2019 pandemic, we briefly present recommendations for the treatment of psoriatic arthritis. In this review, we briefly address the management options and treatment recommendations for patients with psoriatic arthritis during and after the coronavirus disease 2019 pandemic in light of recent scientific publications.

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PublicationOpen Access

Non-pharmaceutical interventions in Turkey and worldwide during COVID-19 pandemic

2021-12-01T00:00:00Z, İlhan, Mustafa Necmi, Tüzün, Hakan, Kılıç, Rahmi, Yıldırım, Nuran, YILDIRIM, NURAN

Nonpharmaceutical interventions (NPIs) are actions apart from getting vaccinated and medications, in order to promote deceleration of the spread of illness among people and communities during pandemic. In this article, we aim to examine NPIs applied in Turkey and worldwide due to the COVID-19 pandemic. Some of the NPIs such as isolation, quarantine, and contact tracing were maintained with updates of the Ministry of Health guidelines in Turkey. Some NPIs including travel and partial or full curfew mobilization restrictions were set in accordance with the various periods by the number of cases. Periods of restrictions at autumn 2021 to summer 2022 are national partial curfews, national extended curfews, local decision-making phase, revised local decision-making phase, partial lockdown, full lockdown and gradual normalization. Mitigation and suppression have been implemented in Turkey with restrictions of varying severity throughout the course of the epidemic. It is seen that the restrictions implemented in Turkey contributed to the flattening of the epidemic curve. Even some countries mainly applied the suppression method, and others applied the mitigation method, in general, it is seen that similar methods were applied with different weights. Examples of different countries demonstrated that NPIs are effective for flattening epidemic curve. NPI have been the main instrument for a year and a half from the beginning of the epidemic to mid-2021 in Turkey as well as worldwide.

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PublicationOpen Access

Phobia of COVID-19 on people who aged 18 and older

2021-01-01T00:00:00Z, ZORLU, MEHMET, Kiskac, Nese, KISKAÇ, MUHARREM, ZORLU, MEHMET, KISKAÇ, MUHARREM

Objectives: Our aim was to evaluate the participants with the COVID-19 scale in order to see the effects of the COVID-19 pandemic on people, which has affected the whole world along with our country, to be able to take the necessary precautions for the current pandemic and similar pandemics and to minimize the negative aspects globally. Methods: A total of 1010 people who aged 18 and older (between the ages of 18-76) were included in the research. Besides from the personal information of people who aged 18 and older such as a city of residence, age, gender, profession, education, the number of people who live in the same house, their chronic illnesses, marital status, and the existence of a child, a 20-question phobia of COVID-19 scale was carried out. The results were 95% reliable, and their significance was evaluated to be on p<0.05 level. Result: The COVID-19 Phobia Scale point for women was 54.97±14.44 while it was 51.28±14.06 for men, and between the two groups, there is a high level of significant difference (p<0.05) statistically, COVID-19 Phobia Scale point of people who have chronic illnesses is 56.51±15.84, meanwhile, the point of people who have no chronic illnesses was found to be 52.96±13.99, and it was detected that this difference was statistically significant (p<0.05). Conclusion: Besides the COVID-19 pandemic affecting the whole society, we see that the women population and people who have chronic illnesses are going through much more fear and anxiety.