Goal: 02 - Açlığa Son
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AMAÇ 2: AÇLIĞA SON
Son 20 yılda hızlı ekonomik büyüme ve tarımsal verimlilikteki artış, yetersiz beslenen insanların sayısında yarıdan fazla azalma sağlamıştır. Eskiden kıtlık ve açlık çeken gelişmekte olan ülkelerin çoğu, en korunmasız kitlelerin beslenme ihtiyaçlarını artık karşılayabiliyor. Orta ve Doğu Asya, Latin Amerika ve Karayipler’de, aşırı açlığın ortadan kaldırılmasında büyük ilerleme kaydedilmiştir.
Sürdürülebilir Kalkınma Amaçları, 2030 yılına kadar açlık ve yetersiz beslenmenin her biçimini sona erdirmeyi, başta çocuklar olmak üzere tüm insanların yıl boyunca yeterli besine sahip olmasını hedefliyor. Amaçlar, küçük çiftçilerin desteklenmesi ve arazi, teknoloji ve piyasalara eşit erişimlerini destekleyen sürdürülebilir tarım uygulamalarının teşvik edilmesini kapsıyor. Aynı zamanda, tarımda verimliliği artırmak için altyapı ve teknolojiye yatırım yapılması alanında uluslararası işbirliğini gerektiriyor. Sürdürülebilir Kalkınma Amaçları kapsamında konulan diğer hedeflerle birlikte, 2030 yılına kadar açlığı ortadan kaldırabiliriz.
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Publication Metadata only Comparative antifungal efficacy of light-activated disinfection and octenidine hydrochloride with contemporary endodontic irrigants(2015-02-01T00:00:00Z) Eldeniz, Ayce Unverdi; Guneser, MEHMET BURAK; Akbulut, Makbule Bilge; GÜNEŞER, MEHMET BURAKThe aim of this study was to evaluate the antifungal effects of light-activated disinfection (LAD) in comparison with contemporary root canal irrigation solutions: sodium hypochlorite and 2 % chlorhexidine gluconate and a new wound antiseptic, octenidine hydrochloride. Seventy extracted teeth having single root canals were contaminated with Candida albicans for 14 days. The samples were divided into five experimental (n = 10) and two control (positive and negative) groups (n = 10): (1) LAD with toluidine blue O, (2) octenidine hydrochloride (OCT), (3) 2.5 % sodium hypochlorite (2.5 % NaOCl), (4) 5.25 % sodium hypochlorite (5.25 % NaOCl) and (5) 2 % chlorhexidine. Five millilitres of each test solution was applied for 3 min, and irradiation time used for LAD was 30 s. After treatment, the dentin chips were collected from inner canal walls into vials containing phosphate buffered saline, vortexed, serially diluted, seeded on Tryptic Soy Agar plates and incubated (37 A degrees C, 48 h). The number of colony-forming units was then counted. Differences between LAD group and positive control group were statistically significant (P < 0.05). All Candida cells were totally eliminated in root canals irrigated with OCT, 2.5 % NaOCl, 5.25 % NaOCl and 2 % chlorhexidine groups (CFU = 0). Within the limitations of this ex vivo study, LAD had minimal antimicrobial effect on C. albicans when used 30 s, and further modifications in LAD protocol are required to improve its antifungal capability. A new wound antiseptic, octenidine hydrochloride, demonstrated better potential than LAD in elimination of Candida albicans cells and may be a promising alternative to NaOCl and chlorhexidine solutions in future.Publication Metadata only Malnutrition in older age(2019-11-01T00:00:00Z) Kalan, Ugur; Arik, Ferhat; Soysal, Pınar; SOYSAL, PINARPublication Metadata only Fatty Acid Methyl Ester Composition of Some Turkish Apiaceae Seed Oils: New Sources for Petroselinic Acid(2016-11-01T00:00:00Z) Kucukboyaci, Nurgun; Ayaz, Fatma; Adiguzel, Nezaket; Bani, Baris; Goren, AHMET CEYHAN; GÖREN, AHMET CEYHANThe seed oils of twenty-six species of Apiaceae belonging to the genera Bunium, Cnidium, Ferula, Ferulago, Heracleum, Hippomarathrztm, Malabaila, Myrrhoides, Olymposciadium, Pimpinella, Prangos, Szovitsia, Trigonasciadium, Trinia and Zosima, collected in Turkey, were investigated for their oil content, and amount of petroselinic acid (PA), as well as for the composition of their fatty acid methyl esters (FAMEs) by GC-MS. Seed oil content ranged from 7.1% in Szovitsia callicarpa to 29.3% in Ferula haussknechtii. The results showed that the seed oils of the studied species contained high amounts of PA (1.2-72.2%), followed by significant amounts of linoleic (LA, 13.8-50.8%) and oleic (OA, 4.2-61.6%) acids. PA was found in all the analyzed species, except for Olymposciadium caespitosum, which belongs to a monotypic endemic genus of the family. According to data from our study, PA was found to be predominantly in the seed oils of Hippomarathrum cristatum (72.2%), Trinia glauca (64.9%) and Bunium microcarpum (59.7%) and, therefore these species might be considered as new sources of PA, and represent a potential oleochemical raw material. This is the first extensive study of the composition of Turkish Apiaceae species. The high amounts of PA may also have chemotaxonomic significance.Publication Open Access Efficacy of glycerol and flax seed oil as anti-adhesive barriers after thyroidectomy.(2014-06-28) IDIZ, O; Aysan, E; FIRAT, D; ERSOY, YELİZ EMİNE; CENGIZ, MB; AKBULUT, H; ISıK, A; MUSLUMANOGLU, M; AYŞAN, MUSTAFA ERHAN; ERSOY, YELIZ EMINEWe evaluated the effects of local flax seed oil and glycerol application for reducing adhesion formation after thyroidectomy. Material/Method: We randomly assigned 18 female Wistar albino rats (median weight: 275 g, median age: 4.5 mth) to 3 groups: 0.1 ml 0.9% NaCl, glycerol, and flax seed oil were sprayed in a perithyroidal area after thyroidectomy operation on all animals as anti-adhesive barriers. Rats were sacrificed on the postoperative 14th day and adhesions were evaluated macroscopically and microscopically. Results: The median macroscopic adhesion score was 3.0±0.0 in the 0.9% NaCl group, 1.33±0.52 in the glycerol group, and 1.67±0.53 in the flax seed oil group. The median histopathological fibrosis scores were 2.33±0.82, 0.67±0.52, and 0.83±0.75, respectively. Both glycerol and flaxseed oil group macroscopic and microscopic scores were significantly lower than the 0.9% NaCl group (p<0.05). There was no significant difference among the groups (p>0.05). Conclusions: Glycerol and flax seed oil both decrease the incidence of post-thyroidectomy adhesion in rats, but glycerol is more effective.Publication Metadata only Malnutrition in elderly patients with renal failure: Importance of pre-dialysis period(2014-10-01) Kazancioglu, RÜMEYZA; CINAR, A.; Soysal, P.; GORCIN, B.; Isik, A. T.; KAZANCIOĞLU, RÜMEYZA; BÜYÜKAYDIN, BANUBackground and aims: In elderly, renal failure is one of the major comorbidities. Malnutrition is another clinical problem in these patients- follow-up. In this study, we compared nutritional states of elderly patients with different renal functions.Publication Open Access Correlation of Brain Neuropeptide (Nesfatin-1 and Orexin-A) Concentrations with Anthropometric and Biochemical Parameters in Malnourished Children(2015-09-01) Kahraman, Feyza Ustabas; Vehapoglu, Aysel; Ozgen, Ilker Tolga; Terzioglu, Sule; Cesur, YAŞAR; Dundaroz, Rusen; VEHAPOĞLU TÜRKMEN, AYSEL; USTABAŞ KAHRAMAN, FEYZA; ÖZGEN, İLKER TOLGA; TERZİOĞLU, ŞULE; CESUR, YAŞAR; İŞCAN, AKINObjective: Malnutrition continues to be a leading cause of stunted growth in many countries. This study aimed to investigate serum nesfatin-1 and orexin-A levels in underweight children and the potential correlations of these levels with anthropometric and nutritional parameters. Methods: The study enrolled 44 prepubertal children (between 2 and 12 years of age) with thinness grades of 1-3 and 41 healthy age- and gender-matched children. The demographic, clinical and laboratory parameters including nesfatin-1 and orexin-A concentrations were compared between the two groups. The correlations of nesfatin-1 and orexin-A with biochemical and anthropometric parameters were investigated. The receiver operating characteristic (ROC) analysis were also performed for evaluating nesfatin-1 and orexin-A in distinguishing children with malnutrition from healthy controls. Results: Thyroid-stimulating hormone, vitamin B12 and insulin levels were significantly lower in the study group than controls (p=0.001, p=0.049 and p=0.033, respectively). Mean nesfatin-1 levels in the malnourished group was also significantly lower compared to the healthy controls (3871.2 ± 1608.8 vs. 5515.0 ± 3816.4 pg/mL, p=0.012). No significant difference was observed in the orexin-A levels between the two groups (malnourished vs. control groups: 1135.7 ± 306.0 vs. 1025.7 ± 361.6 pg/mL, p=0.141). Correlation analyses revealed a positive correlation of nesfatin-1 and a negative correlation of orexin-A with body mass index (BMI) z-score. ROC analysis demonstrated that nesfatin-1 and orexin-A cannot be used to distinguish children with malnutrition from healthy controls (AUC: 0.620, p=0.061 for nesfatin-1 and AUC: 0.584, p=0.190 for orexin-A). Conclusion: The positive correlation of nesfatin-1 and the negative correlation of orexin-A with BMI suggest that these neuropeptides may be a part of a protective mechanism in the maintenance of nutritional status and that they may have a role in regulating food intake in undernourished children.Publication Metadata only Effects of Black Cumin Seed (Nigella sativa) and Garlic (Allium sativum) Extracts on Aluminum Induced Cytotoxicity and Genotoxicity in Human Lymphocyte Culture(2015-09-01T00:00:00Z) Celik, Hakim; KOÇYİĞİT, ABDÜRRAHİM; Bagci, Cahit; Koyuncu, Ismail; Karakilcik, Ali Ziya; KOÇYİĞİT, ABDÜRRAHİMPublication Metadata only Malnutrition and Malnutrition Risk Can Be Associated with Systolic Orthostatic Hypotension in Older Adults.(2018-01-01T00:00:00Z) Kocyıgıt, Se; Soysal, Pınar; Ates, Bulut; Isık, At; SOYSAL, PINARPublication Metadata only Effects of Malnutrition on Neutrophil/Mononuclear Cell Apoptotic Functions in Children with Acute Lymphoblastic Leukemia(2017-04-01) ÇAKIR, FATMA BETÜL; Berrak, Su Gülsün; Aydoğan, Gönül; Tulunay, Aysin; Timur, Cetin; Canpolat, Cengiz; ÇAKIR, FATMA BETÜLBackground: Recent studies claim that apoptosis may explain immune dysfunction observed in malnutrition. Objective: The objective of this study was to determine the effect of malnutrition on apoptotic functions of phagocytic cells in acute lymphoblastic leukemia (ALL). Materials and Methods: Twenty-eight ALL patients (13 with malnutrition) and thirty controls were enrolled. Neutrophil and mononuclear cell apoptosis of ALL patients and the control group were studied on admission before chemotherapy and repeated at a minimum of three months after induction of chemotherapy or when the nutritional status of leukemic children improved. Results: The apoptotic functions of both ALL groups on admission were significantly lower than those of the control group. The apoptotic functions were lower in ALL patients with malnutrition than those in ALL patients without malnutrition, but this was not statistically significant. The repeated apoptotic functions of both ALL groups were increased to similar values with the control group. This increase was found to be statistically significant. Conclusions: The apoptotic functions in ALL patients were not found to be affected by malnutrition. However, after dietary intervention, increased apoptotic functions in both ALL patient groups deserve mentioning. Dietary intervention should always be recommended as malnutrition or cachexia leads to multiple complications. Enhanced apoptosis might originate also from remission state of cancer.Publication Metadata only Fatty Acid Composition of Juniperus Species (Juniperus Section) Native to Turkey(2012-07-01T00:00:00Z) Guvenc, Aysegul; Kucukboyaci, Nurgun; Goren, AHMET CEYHAN; GÖREN, AHMET CEYHANFatty acid compositions of seeds of five taxa of the Juniperus section of the genus Juniperus L. (Cupressaceae), i.e. J. drupacea Lab.. J. communis L. var. communis, J. communis var. saxatilis Pall., J. oxycedrus L. subsp. oxycedrus, and J. oxycedrus subsp. macrocarpa (Sibth. & Sm.) Ball, were investigated. Methyl ester derivatized fatty acids of the lipophylic extracts of the five species were comparatively analyzed by capillary gas chromatography-mass spectrometry (GC-MS). Juniperus taxa showed uniform fatty acid patterns, among which linoleic (25.8-32.5%), pinolenic (11.9-24.1%) and oleic acids (12.4-17.2%) were determined to be the main fractions in the seed oils. Juniperonic acid was found to be remarkably high in J. cumnunis var. saxatilis (11.4 %), J. oxycedrus subsp. oxycedrus (10.4 %), and J. communis var. communis (10.1 %). To the best of our knowledge, the present work discloses the first report on the fatty acid compositions of seeds of this Juniperus section grown in Turkey.