Browsing by Author "Topcu, GÜLAÇTI"
Now showing items 1-20 of 45
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A High-Performance Liquid Chromatographic Method for the Determination of Meropenem in Serum.
Topcu, GÜLAÇTI; Sagirli, O; Dincel, D (2019-11-18){{abstract}} -
A new rapid spectrophotometric method to determine the rosmarinic acid level in plant extracts
Ozturk, Mehmet; Topcu, GÜLAÇTI; Harmandar, Mansur; Ince, Burcu; Duru, Mehmet E. (2010-12-15)A novel spectrophotometric method to determine the amount of rosmarinic acid in unpurified methanol extracts of the plants was developed. Rosmarinic acid is a naturally occurring bioactive compound in plants as an ester ... -
A Novel Isopimarane Diterpenoid with Acetylcholinesterase Inhibitory Activity from Nepeta sorgerae, an Endemic Species to the Nemrut Mountain
Yilmaz, Anil; Topcu, GÜLAÇTI; Goren, Nezhun; Dirmenci, Tuncay; Caglar, Pinar (2012-06-01)From the dichloromethane extract of Nepeta sorgerae, the isolation and structure elucidation are now reported of a new isopimarane diterpenoid, named sorgerolone, and two known triterpenoids, oleanolic acid and ursolic ... -
A promising novel antidiabetic compound: Alysine-A
Yilmaz, ANIL; Sen, A.; Ayar, B.; Topcu, GÜLAÇTI (2016-09-01) -
Abietane diterpenoids as butyrylcholinesterase inhibitors from Salvia species
Öztürk, Mahmut Serdar; Akdemir, ATİLLA; Topcu, GÜLAÇTI; Kola, U.; Boğa, Miray (2012-08-01) -
Anti-neuroinflammatory effect of butanolic subextract of Capparis ovata water extract used as an alternative and complementary treatment for multiple sclerosis
Hacibekiroglu, Isil; Sen, Alaattin; Arslan, Sevki; Celik, Gurbet; Kolak, Ufuk; Topcu, GÜLAÇTI; Ozgun, Ozden (2014-10-15) -
ANTIOXIDANT ACTIVITY AND FLAVONOIDS OF Stachys ocymastrum
KABOUCHE, Zahia; Topcu, GÜLAÇTI; KABOUCHE, Ahmed; LAGGOUNE, Souheila; LAKHAL, Hichem; BOUDIAR, Tarek (2011-01-01) -
Antioxidant and anticholinesterase active constituents from Micromeria cilicica by radical-scavenging activity-guided fractionation
CHOUDHARY, M. Iqbal; Oksuz, Sevil; Kolak, Ufuk; Topcu, GÜLAÇTI; Ozturk, Mehmet (2011-05-01)From the acetone extract of Micromeria cilicica, two new (1 and 2) and five known (3-7) compounds were obtained through radical-scavenging activity guided isolation. Structures of the compounds were identified as piperitone ... -
Antioxidant and toxicological in-vivo and in-vitro examination of licorice extract
Guler, E. M.; Bektay, MUHAMMED YUNUS; Topcu, GÜLAÇTI; Bayindir, NİHAN; Uckaya, FATİH; Esrefoglu, MUKADDES; Kocyigit, ABDÜRRAHİM (2016-09-01) -
Antioxidant and Tyrosinase Inhibitory Activities of Flavonoids from Trifolium nigrescens Subsp petrisavi
Demirkiran, Ozlem; Topcu, GÜLAÇTI; Ozturk, Mehmet; Sabudak, Temine (2013-12-25)Trifolium nigrescens was researched for its chemical constituents for the first time. Bioassay-guided isolation of the EtOAc extract from the leaves of T. nigrescens resulted in the purification of a new biflavone, 4-,5,5 ... -
Antioxidant, anticholinesterase, and antimicrobial activities and fatty acid constituents of Achillea cappadocica Hausskn. et Bornm.
Ertas, Abdulselam; GOREN, AHMET CEYHAN; Topcu, GÜLAÇTI; Kolak, Ufuk; Hasimi, Nesrin; Boga, Mehmet; Yesil, Yeter (2014-01-01)This study was the first fatty acid analysis and biological activity report on an endemic Achillea species, Achillea cappadocica Hausskn. et Bornm. The major compounds in the fatty acid were identified as oleic (34.7%), ... -
Bioassay-guided isolation, identification of compounds from Origanum rotundifolium and investigation of their antiproliferative and antioxidant activities.
SEN, O; ERENLER, R; EMINAGAOGLU, O; AYDIN, A; ELMASTAS, M; Topcu, GÜLAÇTI; MERAL, B (2017-12-01)Context: Origanum (Lamiaceae) has been used in food and pharmaceutical industries. Objective: Isolation and identification of bioactive compounds from Origanum rotundifolium Boiss. and investigation of their antiproliferative ... -
Capparis ovata treatment suppresses inflammatory cytokine expression and ameliorates experimental allergic encephalomyelitis model of multiple sclerosis in C57BL/6 mice
Ergur, Bekir U.; Gazioglu, IŞIL; Sen, Alaattin; Celik-Turgut, Gurbet; Kolak, Ufuk; Ozbal, Seda; Arslan, Sevki; Ozgun-Acar, Ozden; Topcu, GÜLAÇTI (2016-09-15)Since ancient times, Capparis species have been widely used in traditional medicine to treat various diseases. Our recent investigations have suggested Capparis ovata-s potential anti-neuroinflammatory application for the ... -
Capparis ovate ameliorates experimental allergic encephalomyelitis model of multiple sclerosis in C57BL/6 mice
Kolat, U.; Gazioglu, IŞIL; Sen, A.; Ozgun, O.; Ozbal, S.; Topcu, GÜLAÇTI; Turgut, G. C.; Ergur, B. U.; Arslan, S. (2015-09-01) -
Characterization of the Chemical Profile of Euphorbia Species from Turkey by Gas Chromatography-Mass Spectrometry (GC-MS), Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS), and Liquid Chromatography-Ion Trap-Time-of-Flight-Mass Spectrometry (LC-IT-TOF-MS) and Chemometric Analysis
Olmez, Ozge Tokul; Yener, Ismail; Ertas, Abdulselam; Yılmaz, Mustafa Abdullah; Yilmaz, Pelin Koseoglu; Yesil, Yeter; Kaplaner, Erhan; Ozturk, Mehmet; Temel, Hamdi; Kolak, Ufuk; Topcu, GÜLAÇTI (2019-05-03)The Euphorbiaceae family comprises of about 300 genera and 5000 species primarily distributed in America and tropical Africa. The Euphorbia genus is represented by 105 species and locally named as -Sutlegen- and -Xasil- ... -
Chemical Characterization of 64 Propolis Samples from Hakkari, Turkey
Bayram, Nesrin Ecem; Topcu, GÜLAÇTI; SALİH, BEKİR; Oz, Gul Cevahir; SORKUN, KADRİYE (2018-11-01)Propolis is a resinous substance produced by honey bees from various plants they visit. Sixty-four propolis samples were collected from different localities of four districts (Merkez, Yiiksekova, Semdinli, and Qukurca) in ... -
Chemical Composition of Natural Colophony from Pinus brutia and Comparison with Synthetic Colophony
GOREN, Ahmet C.; Ozturk, Alp Hakan; BILSEL, Gokhan; Topcu, GÜLAÇTI (2010-11-01)The compositions of colophony resins obtained from Pinus brutia Ten trees by three different methods (acid paste, carved hole and scraping) from Ayvacik, Gokova and Kemalpasa in Turkey were analyzed by capillary GC-MS The ... -
Chemical composition of the essential oil and hexane extract of Salvia chionantha and their antioxidant and anticholinesterase activities
Ozturk, Mehmet; Topcu, GÜLAÇTI; Harmandar, Mansur; Mehmet, Emin Duru; Tel, Gulsen (2010-11-01)The essential oil and methyl ester of hexane extract of Salvia chionantha Boiss. were analysed by GC and GC-MS. Totally, 54 components were detected in the essential oil and all of them were fully determined. Germacrene D ... -
Chemical Constituents of Two Endemic Sideritis Species from Turkey with Antioxidant Activity
Carikci, Sema; Topcu, GÜLAÇTI; Azizoglu, Akin; Kilic, Turgut (2012-01-01)In this study, two Sideritis species, endemic to Turkey, S. niveotomentosa Huber - Morathii, S. brevidens P. H. Davis have been studied for their diterpenic compounds and the antioxidant properties. Eight known diterpenoids, ... -
Chemical Profile and Biological Activities of Two Edible Plants: Chemical Investigation and Quantitative Analysis Using Liquid Chromatography Tandem Mass Spectrometry and Gas Chromatography Mass Spectrometry
Boga, Mehmet; Yesil, Yeter; Ertas, Abdulselam; Yilmaz, Mustafa Abdullah; Hasimi, Nesrin; Topcu, GÜLAÇTI; GOREN, Ahmet C.; Temel, Hamdi (2016-01-02)The objectives of this study were to define the phenolic and fatty acid profiles, anticholinesterase, antioxidant, antimicrobial activities, and total phenolic-flavonoid contents of Lycopsis orientalis and Tragopogon ...
