Browsing by Author "Tekkeli, Serife Evrim Kepekci"
Now showing items 1-13 of 13
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A New HPLC Method with Fluorescence Detection for the Determination of Memantine in Human Plasma
Tekkeli, Serife Evrim Kepekci; Toker, Sidika Erturk (2013-01-01)A sensitive and selective HPLC method with fluorometric detection was developed for the determination of memantine in human plasma and applied to a pharmacokinetic study. Memantine was precolumn derivatized with 9-fluorenylmethyl ... -
A Review of Current Methods for the Determination of Acrylamide in Food Products
Tekkeli, Serife Evrim Kepekci; Onal, Cem; Onal, Armagan (2012-02-01)Acrylamide (AA) is a potentially carcinogenic substance which is formed during heating of food products containing carbohydrates and asparagine. It was first detected in food products in 2002. Since that time, several ... -
A review of the liquid chromatographic methods for the determination of biogenic amines in foods
Onal, Armagan; Tekkeli, Serife Evrim Kepekci; Onal, Cem (2013-05-01)Biogenic amines (BAs) are biologically active molecules which have aliphatic (putrescine, cadaverine, spermine, spermidine), aromatic (tyramine, phenylethylamine) or heterocyclic (histamine, tryptamine) structures. They ... -
Current HPLC Methods for Assay of Nano Drug Delivery Systems
KIZILTAS, Mustafa Volkan; Tekkeli, Serife Evrim Kepekci (2017-01-01)In nano drug formulations the mechanism of release is a critical process to recognize controlled and targeted drug delivery systems. In order to gain high bioavailability and specificity from the drug to reach its therapeutic ... -
Determination of atorvastatin in human plasma by magnetic solid-phase extraction combined with HPLC and application to a pharmacokinetic study
Onal, Armagan; Tekkeli, Serife Evrim Kepekci; Durmus, ZEHRA (2016-01-01)A simple and sensitive analytical procedure by solid-phase extraction method combined with high-performance liquid chromatography and using of graphene-magnetite nanomaterials as sorbent has been developed for the determination ... -
Development and validation of a HPLC method for the determination of benzo(a)pyrene in human breast milk
Tekkeli, Serife Evrim Kepekci; Gazioglu, IŞIL (2017-04-01)A simple analytical procedure was developed for the quantitation of benzo(a)pyrene in human breast milk using solid phase extraction (SPE) combined with high performance liquid chromatography. Before the chromatographic ... -
Development and Validation of Spectrophotometric Methods for the Determination of Rasagiline in Pharmaceutical Preparations
Onal, Armagan; Bahadori, FATEMEH; Tekkeli, Serife Evrim Kepekci (2013-01-01)This study presents three simple, rapid, and accurate spectrophotometric methods for the determination of Rasagiline (RSG) in pharmaceutical preparations. The determination procedures depend on the reaction of RSG with ... -
Development of an HPLC-UV Method for the Analysis of Drugs Used for Combined Hypertension Therapy in Pharmaceutical Preparations and Human Plasma
Tekkeli, Serife Evrim Kepekci (2013-01-01)A simple, rapid, and selective HPLC-UV method was developed for the determination of antihypertensive drug substances: amlodipine besilat (AML), olmesartan medoxomil (OLM), valsartan (VAL), and hydrochlorothiazide (HCT) ... -
Extractive Spectrophotometric Method for the Determination of Lamivudine and Zidovudine in Pharmaceutical Preparations Using Bromocresol Purple
Tekkeli, Serife Evrim Kepekci (2013-01-01)A new spectrophotometric method has been established for the quantitation of lamivudine (LVD) and zidovudine (ZVD) in pharmaceutical preparations. The method is based on the reaction between the investigated drug substances ... -
LIQUID CHROMATOGRAPHIC ANALYSIS OF CAROTENOIDS IN FOODS
Onal, Cem; DİNCEL, DEMET; Sagirli, Olcay; Tekkeli, Serife Evrim Kepekci; Onal, Armagan (2019-06-01)Current scientific studies indicate that carotenoids (CRTDs) are beneficial for maintaining health and lowering the risk of different pathologies. Considering the increasing role of carotenoids in healthcare, determination ... -
Spectrofluorimetric determination of tobramycin in human serum and pharmaceutical preparations by derivatization with fluorescamine
Onal, Armagan; Tekkeli, Serife Evrim Kepekci; Sagirli, Olcay (2014-02-01) -
Spectrofluorimetric Methods for the Determination of Gemifloxacin in Tablets and Spiked Plasma Samples
Tekkeli, Serife Evrim Kepekci; Onal, Armagan (2011-05-01)Two new, sensitive and selective spectrofluorimetric methods have been developed for the determination of gemifloxacin (GFX) in tablets and spiked plasma samples. Gemifloxacin, as a primary amine compound, reacts with ... -
THE EFFECT OF DIFFERENT RETINA DISEASES ON CHOLESTEROL AND FATTY ACID CONTENT OF SILICONE OIL FROM VITRECTOMIZED EYES
GUNGEL, Hulya; Tekkeli, Serife Evrim Kepekci (2016-06-01)The differences of cholesterol and fatty acid content of silicone oils that were removed from vitrectomized eyes due to different retinal diseases were investigated. The silicone oils were removed from 25 cases after 4-8 ...
