Browsing by Author "Supuran, CT"
Design, synthesis and biological activity of selective hCAs inhibitors based on 2-(benzylsulfinyl)benzoic acid scaffold. De, Filippis; Rotondi, G; Guglielmi, P; De, Monte; Carradori, S; Secci, D; Supuran, CT; Maccallini, C; Akdemir, ATİLLA; Amoroso, R; Cirilli, R; Angeli, A (2019-12-01)A large library of derivatives based on the scaffold of 2-(benzylsulfinyl)benzoic acid were synthesised and tested as atypical inhibitors against four different isoforms of human carbonic anhydrase (hCA I, II, IX and XII, ...
Güzel-Akdemir, Ö; Carradori, S; Grande, R; Demir-Yazıcı, K; Akdemir, ATİLLA; Angeli, A; Supuran, CT (2020-04-22)In our efforts to find new and selective thiazolidinone-based anti-Candida agents, we synthesized and tested 26 thiazolidinones against several Candida spp. and Gram-positive and Gram-negative bacteria. The compounds ...
Potent inhibitors of mitochondrial carbonic anhydrase isozymes CA-VA and CA-VB and brain-associated CA-VII AKDEMİR, ATİLLA; Güzel, Özlen; Supuran, CT (2012-04-15)