Browsing by Author "Sonmez, Fatih"
Now showing items 1-20 of 21
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Antioxidant activities of novel eugenol derivatives substituted carbamate
Yanıkoğlu, RABİA SARE; ZENGİN KURT, BELMA; GAZİOĞLU, IŞIL; Sonmez, Fatih (2015-11-29) -
Design, synthesis and docking study of novel coumarin ligands as potential selective acetylcholinesterase inhibitors
Sonmez, Fatih; KURT, Belma Zengin; Gazioglu, IŞIL; BASILE, Livia; Dag, AYDAN; CAPPELLO, Valentina; GINEX, Tiziana; Kucukislamoglu, Mustafa; GUCCIONE, Salvatore (2017-01-01)New coumaryl-thiazole derivatives with the acetamide moiety as a linker between the alkyl chains and/or the heterocycle nucleus were synthesized and in vitro tested as acetylcholinesterase (AChE) inhibitors. 2-(diethylam ... -
In vitro biological screening of ten edible plants from middle black sea region
ZENGİN KURT, BELMA; GAZİOĞLU, IŞIL; SEVGİ, ECE; Sonmez, Fatih (2015-11-27) -
In vitro inhibition effects on erythrocyte carbonic anhydrase I and II and structure-activity relationships of cumarylthiazole derivatives
Kurt, BELMA; Sonmez, Fatih; GÖKÇE, Başak; Ergun, Adem; Gencer, Nahit; Demir, Taki; Arslan, Oktay; Kucukislamoglu, Mustafa (2016-09-01)Coumarin and heterocyclic compounds incorporating urea have clinical applications as antiepileptics, diuretics, and antiglaucoma agents due to their carbonic anhydrase inhibitory properties. We investigated inhibition of ... -
Novel coumarin derivatives as selective acetylcholinesterase inhibitors
Basile, Livia; ZENGİN KURT, BELMA; GAZİOĞLU, IŞIL; Sonmez, Fatih; Küçükislamoğlu, Mustafa; Ginex, Tiziana; Cappello, Valentino; Guccione, Salvatore (2015-09-09) -
Optimization of ultrasound-assisted extraction of total phenolic contents and antioxidant activity using response surface methodology from jujube leaves (Ziziphus jujuba) and evaluation of anticholinesterase inhibitory activity
Zemouri-Alioui, Salima; Louaileche, Hayette; Bey, Mostapha Bachir; Kurt, BELMA; Sonmez, Fatih (2019-03-01)An ultrasound-assisted procedure for the extraction of phenolics (TPC) and antioxidant activity (AA) from jujube leaves have been investigated using response surface methodology (RSM). The Box-Behnken design was used to ... -
Potential of aryl-urea-benzofuranylthiazoles hybrids as multitasking agents in Alzheimer-s disease
Kurt, BELMA; Gazioglu, IŞIL; BASILE, Livia; Sonmez, Fatih; GINEX, Tiziana; Kucukislamoglu, Mustafa; GUCCIONE, Salvatore (2015-09-18)New benzofuranylthiazole derivatives containing the aryl urea moiety were synthesized and evaluated in vitro as dual acetylcholinesterase (AChE)-butyrylcholinesterase (BuChE) inhibitors. In addition, the cupric reducing ... -
Quinoline-sulfamoyl carbamates/sulfamide derivatives: Synthesis, cytotoxicity, carbonic anhydrase activity, and molecular modelling studies.
Zengin Kurt, Belma; Cakmak, Elmas Begum; Ozturk Civelek, DİLEK; Angeli, Andrea; Akdemir, Atilla; Sonmez, Fatih; Supuran, Claudiu T; Kucukislamoglu, Mustafa (2021-02-24) -
Synthesis and aflatoxin B1 inhibitory activities of novel coumarin derivatives substituted carbamate
Çamlık, Gamze; ZENGİN KURT, BELMA; GAZİOĞLU, IŞIL; Sonmez, Fatih (2015-11-27) -
Synthesis and Anticholinesterase Activity of Eugenol Derivatives
ZENGİN KURT, BELMA; Sonmez, Fatih; Küçükislamoğlu, Mustafa (2017-05-07) -
Synthesis and biological evaluation of novel coumarin-chalcone derivatives containing urea moiety as potential anticancer agents
Kurt, BELMA; Kandas, Nur Ozten; DAĞ, AYDAN; Sonmez, Fatih; Kucukislamoglu, Mustafa (2020-01-01)The increasing interest on new drug discovery is constantly up to date as drugs do not increase survival adequately against increasing cancer cases worldwide. Based on the reported anticancer activity of coumarin, chalcone ... -
Synthesis of Biologically Active Novel Coumarin Derivatives
Özten, Özge; ZENGİN KURT, BELMA; Sonmez, Fatih; Gülgeç, Ahmet Sadık; Küçükislamoğlu, Mustafa (2017-04-29) -
Synthesis of Biologically Active Novel Pyrrole Derivatives Containing Urea
Özbilge, Ayşegül; ZENGİN KURT, BELMA; Sonmez, Fatih (2017-04-29) -
Synthesis, anticholinesterase activity and molecular modeling study of novel carbamate-substituted thymol/carvacrol derivatives
KURT, Belma Zengin; Gazioglu, IŞIL; Dag, AYDAN; Salmas, Ramin Ekhteiari; Kayik, Gulru; Durdagi, Serdar; Sonmez, Fatih (2017-02-15)New thymol and carvacrol derivatives with the carbamate moiety were synthesized and their inhibitory effects on acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) were evaluated. 5-isopropyl-2-methylphenyl(3-f ... -
Synthesis, Anticholinesterase, Antioxidant, and Anti-Aflatoxigenic Activity of Novel Coumarin Carbamate Derivatives
Gazioglu, IŞIL; KURT, Belma Zengin; KANDAS, Nur Ozten; Sonmez, Fatih (2018-04-17)New coumarin derivatives with the carbamate moiety were synthesized and their inhibitory effects on acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) were evaluated. 4-methyl-2-oxo-2H-chromen-7-yl cycloheptylcarbamate ... -
Synthesis, antioxidant and anticholinesterase activities of novel coumarylthiazole derivatives
Kurt, BELMA; Gazioglu, IŞIL; Sonmez, Fatih; Kucukislamoglu, Mustafa (2015-04-01)A newly series of coumarylthiazole derivatives containing aryl urea/thiourea groups were synthesized and their inhibitory effects on acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) were evaluated. The result ... -
Synthesis, antioxidant and carbonic anhydrase I and II inhibitory activities of novel sulphonamide-substituted coumarylthiazole derivatives
Kurt, BELMA; Sonmez, Fatih; Bilen, Cigdem; Ergun, Adem; Gencer, Nahit; Arslan, Oktay; Kucukislamoglu, Mustafa (2016-01-01)New secondary benzenesulphonamide-substituted coumarylthiazole derivatives were synthesized and their inhibitory effects on purified carbonic anhydrase I and II were evaluated using CO2 as a substrate. The result showed ... -
Synthesis, Biological Activitiy for Carvacrol-amide Derivatives as Cholinesterase Inhibitors
Sonmez, Gülşen; ZENGİN KURT, BELMA; Sonmez, Fatih (2017-04-29) -
Synthesis, Biological Activity and Multiscale Molecular Modeling Studies for Coumaryl-carboxamide Derivatives as Selective Carbonic Anhydrase IX Inhibitors
Supuran, Claudiu T.; ZENGİN KURT, BELMA; Sonmez, Fatih; Durdağı, Serdar; Aksoydan, Busecan; Angeli, Andrea; Küçükislamoğlu, Mustafa (2017-08-01)New coumaryl-carboxamide derivatives with the thiourea moiety as a linker between the alkyl chains and/or the heterocycle nucleus were synthesized and their inhibitory activity against the human carbonic anhydrase (hCA) ... -
Three novel Cu(II), Cd(II) and Cr(III) complexes of 6-Methylpyridine-2-carboxylic acid with thiocyanate: Synthesis, crystal structures, DFT calculations, molecular docking and alpha-Glucosidase inhibition studies
Avci, Davut; Alturk, Sumeyye; Sonmez, Fatih; Tamer, Omer; Basoglu, Adil; Atalay, Yusuf; Kurt, BELMA; Dege, Necmi (2018-12-13)Novel complexes of 6-methylpyridine-2-carboxylic acid and thiocyanate ([Cu(NCS)(6-mpa)(2)], (1); [Cd(NCS)(6-mpa)](n), (2); [Cr(NCS)(6-mpa)(2)center dot H2O], (3)} were synthesized, and their structures were characterized ...
