Browsing by Author "SONMEZ, Fatih"

Now showing items 1-2 of 2

Synthesis, anticholinesterase activity and molecular modeling studies of novel carvacrol-substituted amide derivatives

Durdagi, Serdar; Kurt, BELMA; SONMEZ, Fatih; Salmas, Ramin Ekhteiari; Celebi, Gulsen (2019-04-19)

In the present study, 23 novel carvacrol derivatives involving the amide moiety as a linker between the alkyl chains and/or the heterocycle nucleus were synthesized and tested in vitro as acetylcholinesterase (AChE) and ...
Synthesis, biological activity and multiscale molecular modeling studies of bis-coumarins as selective carbonic anhydrase IX and XII inhibitors with effective cytotoxicity against hepatocellular carcinoma

Durdagi, Serdar; Supuran, Claudiu T.; Nocentini, Alessio; Dogan, Berna; Angeli, Andrea; Kurt, BELMA; Dag, AYDAN; SONMEZ, Fatih (2019-06-01)

A series of novel bis-coumarin derivatives containing triazole moiety as a linker between the alkyl chains was synthesized and their inhibitory activity against the human carbonic anhydrase (hCA) isoforms I, II, IX and XII ...