Browsing by Author "Koyuncu, Ismail"
Now showing items 1-9 of 9
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Antigenotoxic and antioxidant potentials of newly derivatized compound naringenin-oxime relative to naringenin on human mononuclear cells
Taskin, Abdullah; Bahadori, FATEMEH; Turkkan, Baki; Dikilitas, Murat; Koyuncu, Ismail; Kocyigit, ABDÜRRAHİM (2016-01-02)We investigated antigenotoxic and antioxidative effects of newly derivatized compound naringenin-oxime (NG-Ox) compared to its mother compound naringenin (NG) against oxidative damage induced by hydrogen peroxide (HP) in ... -
Assessment of the antiproliferative and apoptotic roles of sulfonamide carbonic anhydrase IX inhibitors in HeLa cancer cell line
Gonel, Ataman; Yuksekdag, Ozgur; KOÇYİĞİT, ABDÜRRAHİM; Durgun, Mustafa; Koyuncu, Ismail; Supuran, Claudiu T. (2019-01-01)Carbonic anhydrase IX (CA IX) has recently been validated as an antitumor/antimetastatic drug target. In this study, we examined the underlying molecular mechanisms and the anticancer activity of sulfonamide CA IX ... -
Comparison of cytotoxic, genotoxic and apoptotic effects of naringenin-oxime with its mother compound naringenin on human normal and tumor derived cell lines
Koyuncu, Ismail; KOÇYİĞİT, ABDÜRRAHİM; Turkkan, Baki; BAHADORİ, FATEMEH; Dikilitas, Murat (2015-08-01) -
Cytotoxic, genotoxic and apoptotic effects of naringenin-oxime relative to naringenin on normal and cancer cell lines
Koyuncu, Ismail; BAHADORİ, FATEMEH; KOÇYİĞİT, ABDÜRRAHİM; Turkkan, Baki; Dikilitas, Murat (2016-10-01) -
Diagnostic potential of Brucella melitensis Rev1 native Omp28 precursor in human brucellosis
Koyuncu, Ismail; Karsen, Hasan; Kirmit, Adnan; Kocyigit, ABDÜRRAHİM; Ozer, Ahmet; SELEK, Sahabettin (2018-01-01)Serologic tests for brucellosis aim to detect antibodies produced against membranous lipopolysaccharide of bacteria. Diagnostic use of this method is limited due to false positiveness. This study evaluates an alternative ... -
Effects of Black Cumin Seed (Nigella sativa) and Garlic (Allium sativum) Extracts on Aluminum Induced Cytotoxicity and Genotoxicity in Human Lymphocyte Culture
Celik, Hakim; KOÇYİĞİT, ABDÜRRAHİM; Karakilcik, Ali Ziya; Koyuncu, Ismail; Bagci, Cahit (2015-09-01) -
Phyotherapeutic Properties of Urfa Pistachio Nuts (Pistacia vera L.)
Koyuncu, Ismail; SELEK, ŞAHBETTİN; Dikme, Resat; KOÇYİĞİT, ABDÜRRAHİM (2018-07-01)According to recent studies, the Urfa pistachio nut (Pistacia vera L.) is a rich source of phenolic components, with a high level of the three antioxidant substances of gallic acid, catechin, and epicatechin present together. ... -
Selective inhibition of carbonic anhydrase-IX by sulphonamide derivatives induces pH and reactive oxygen species-mediated apoptosis in cervical cancer HeLa cells
Koyuncu, Ismail; Supuran, Claudiu T.; Durgun, Mustafa; Temiz, Ebru; Gonel, Ataman; KOÇYİĞİT, ABDÜRRAHİM (2018-12-01)Selective inhibition with sulphonamides of carbonic anhydrase (CA) IX reduces cell proliferation and induces apoptosis in human cancer cells. The effect on CA IX expression of seven previously synthesised sulphonamide ... -
The evaluation of antioxidant and anticancer effects of Lepidium Sativum Subsp Spinescens L. methanol extract on cancer cells
Koyuncu, Ismail; ÇAĞLAR, HİFA GÜLRU; Gonel, Ataman; Yilmaz, Mustafa Abdullah; Bektas, Ibrahim; Selek, Sahabettin; Akyuz, ENES (2018-01-01)
