Browsing by Author "Koparal, Ayse Tansu"
Anti-lung Cancer and Anti-angiogenic Activities of New Designed Boronated Phenylalanine Metal Complexes Koparal, Ayse Tansu; Bostancioglu, Rakibe Beklem; Benkli, KADRİYE; Varol, Mehmet (2018-01-01)Background: Drug design and discovery studies still remain of great importance in the search for more convenient chemotherapeutic to avoid the drug resistance, systemic toxicity or the long-term side effects.
Studies on the cytotoxic, apoptotic and antitumoral effects of Au(III) and Pt(II) complexes of 1, 10-phenanthroline on V79 379A and A549 cell lines Isik, Kenan; Koparal, Ayse Tansu; Benkli, Kadriye; Genc, Hatice; Bostancioglu, R. Beklem (2012-06-01)In the present study, Au(III) and Pt(II) complexes of 1, 10-phenanthroline (phen) were synthesized and used as the test compounds. The structure elucidation of the synthesized compounds was performed by IR, H-1-NMR and ...
The in vitro assessment of dipyridophenazine complexes in H-ras oncogene transformed rat embryo fibroblast 5RP7 cell line Benkli, KADRİYE; Kaplan, Ayse; Koparal, Ayse Tansu (2018-10-01)Purpose The aim of this study is to detect apoptotic and cytotoxic/antiproliferative effects of a ligand substance and its metal derivatives. The substances were investigated by using an h-ras oncogene transformed rat ...