Browsing by Author "Kolak, Ufuk"
Now showing items 1-20 of 27
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A potential therapeutic role in multiple sclerosis for stigmast-5,22-dien-3 beta-ol myristate isolated from Capparis ovata
Acar, Ozden Ozgun; GAZİOĞLU, IŞIL; Kolak, Ufuk; Sen, Alaattin; TOPÇU, GÜLAÇTI (2017-07-01)Multiple sclerosis (MS) is an autoimmune disease of the human central nervous system. It is one of the most common neurological disorders around the world and there is still no complete cure for MS. Purification of a ... -
Anti-neuroinflammatory effect of butanolic subextract of Capparis ovata water extract used as an alternative and complementary treatment for multiple sclerosis
Sen, Alaattin; Topcu, GÜLAÇTI; Ozgun, Ozden; Kolak, Ufuk; Hacibekiroglu, Isil; Celik, Gurbet; Arslan, Sevki (2014-10-15) -
Anticholinesterase and Antioxidant Activities of Natural Abietane Diterpenoids with Molecular Docking Studies
TOPÇU, GÜLAÇTI; AKDEMİR, ATİLLA; Kolak, Ufuk; Ozturk, Mehmet; Boga, Mehmet; BAHADORİ, FATEMEH; Cakmar, Seda Damla Hatipoglu (2020-01-01)Background: Alzheimer-s Disease (AD) is one of the most prevalent causes of dementia in the world, and no drugs available that can provide a complete cure. Cholinergic neurons of the cerebral cortex of AD patients are lost ... -
Antioxidant Activities of Salvia heldreichiana Boiss. Ex Bentham’s Extracts
Sındırgılı, Burcu; BÜTÜN, BURCU; Kolak, Ufuk; Başkan, Tuba; TOPÇU, GÜLAÇTI (2011-09-11) -
Antioxidant and anticholinesterase active constituents from Micromeria cilicica by radical-scavenging activity-guided fractionation
Ozturk, Mehmet; Kolak, Ufuk; Topcu, GÜLAÇTI; Oksuz, Sevil; CHOUDHARY, M. Iqbal (2011-05-01)From the acetone extract of Micromeria cilicica, two new (1 and 2) and five known (3-7) compounds were obtained through radical-scavenging activity guided isolation. Structures of the compounds were identified as piperitone ... -
Antioxidant and anticholinesterase activities of eleven edible plants
Boga, Mehmet; Hacibekiroglu, IŞIL; Kolak, Ufuk (2011-03-01)Objective: The antioxidant potential and anticholinesterase activity of eleven edible plants were investigated. -
Antioxidant and Anticholinesterase Constituents from the Petroleum Ether and Chloroform Extracts of Iris suaveolens
Hacibekiroglu, IŞIL; Kolak, Ufuk (2011-04-01)The aim of this study was to investigate the phytochemical, antioxidant and anticholinesterase activities of Iris suaveolens. After determining total phenolic and flavonoid contents of the petroleum ether, chloroform and ... -
Antioxidant, anticholinesterase, and antimicrobial activities and fatty acid constituents of Achillea cappadocica Hausskn. et Bornm.
Ertas, Abdulselam; Boga, Mehmet; Hasimi, Nesrin; Yesil, Yeter; GOREN, AHMET CEYHAN; Topcu, GÜLAÇTI; Kolak, Ufuk (2014-01-01)This study was the first fatty acid analysis and biological activity report on an endemic Achillea species, Achillea cappadocica Hausskn. et Bornm. The major compounds in the fatty acid were identified as oleic (34.7%), ... -
Capparis ovata treatment suppresses inflammatory cytokine expression and ameliorates experimental allergic encephalomyelitis model of multiple sclerosis in C57BL/6 mice
Ozgun-Acar, Ozden; Celik-Turgut, Gurbet; Gazioglu, IŞIL; Kolak, Ufuk; Ozbal, Seda; Ergur, Bekir U.; Arslan, Sevki; Sen, Alaattin; Topcu, GÜLAÇTI (2016-09-15)Since ancient times, Capparis species have been widely used in traditional medicine to treat various diseases. Our recent investigations have suggested Capparis ovata-s potential anti-neuroinflammatory application for the ... -
Characterization of the Chemical Profile of Euphorbia Species from Turkey by Gas Chromatography-Mass Spectrometry (GC-MS), Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS), and Liquid Chromatography-Ion Trap-Time-of-Flight-Mass Spectrometry (LC-IT-TOF-MS) and Chemometric Analysis
Yener, Ismail; Ertas, Abdulselam; Yılmaz, Mustafa Abdullah; Olmez, Ozge Tokul; Yilmaz, Pelin Koseoglu; Yesil, Yeter; Kaplaner, Erhan; Ozturk, Mehmet; Temel, Hamdi; Kolak, Ufuk; Topcu, GÜLAÇTI (2019-05-03)The Euphorbiaceae family comprises of about 300 genera and 5000 species primarily distributed in America and tropical Africa. The Euphorbia genus is represented by 105 species and locally named as -Sutlegen- and -Xasil- ... -
Chemical Composition of The Essential Oils of Three Centaurea Species Growing Wild in Anatolia and Their Anticholinesterase Activities
Ertas, Abdulselam; Goren, AHMET CEYHAN; Boga, Mehmet; DEMİRCİ, SERPİL; Kolak, Ufuk (2014-09-03)This report represents the first study on the chemical composition of essential oil of endemic Centaurea lycopifolia. This report also represents the first study on the anticholinesterase activity of essential oils of C. ... -
Chemical profile and biological activities of Veronica thymoides subsp pseudocinerea
Ertas, Abdulselam; Boga, Mehmet; Kizil, Murat; Ceken, Bircan; GOREN, AHMET CEYHAN; Hasimi, Nesrin; Demirci, Serpil; Topcu, GÜLAÇTI; Kolak, Ufuk (2015-03-01)Context: In Turkey, Veronica species (Plantaginaceae) have been used as a diuretic and for wound healing in traditional medicine. Objective: To examine the fatty acid and essential oil profiles, the antioxidant, ... -
Chemical Profile of Malva Neglecta and Malvella Sherardiana by LC-MS/MS, GC/MS and Their Anticholinesterase, Antimicrobial and Antioxidant Properties With Aflatoxin-Contents
Hasimi, Nesrin; Ertas, Abdulselam; Oral, Elif Varhan; Yener, Ismail; Yener, Ismail; Alkan, Huseyin; Boga, Mehmet; Yilmaz, Mustafa Abdullah; Gazioglu, IŞIL; Ozaslan, Cumali; AKDENIZ, Mehmet; Kolak, Ufuk (2017-01-01)The purpose of the present work was to determine the phenolic and the fatty acids profiles by LC-MS/MS and GC/MS with their antioxidant, anticholinesterase and antimicrobial activities, and aflatoxin contents of Malva ... -
Effect of roasting on antioxidant and anticholinesterase capacities of coffee
Yilmaz, Pelin Koseoglu; Hacibekiroglu, IŞIL; Kolak, Ufuk (2014-01-01)The aim of the study was to investigate the effect of the roasting degree on total phenolic and flavonoid contents, antioxidant and anticholinesterase activities of the hexane, acetone, ethanol and water extracts of coffee. ... -
Essential oil compositions and anticholinesterase activities of two edible plants Tragopogon latifolius var. angustifolius and Lycopsis orientalis
Ertas, Abdulselam; Goren, AHMET CEYHAN; Boga, Mehmet; Yesil, Yeter; Kolak, Ufuk (2014-01-01)This is the first report in the literature on essential oil compositions of Tragopogon latifolius var. angustifolius and Lycopsis orientalis which were analysed by using GC-FID and GC-MS techniques. The main constituents ... -
Evaluation of Antioxidant, Cholinesterase Inhibitory and Antimicrobial Properties of Mentha longifolia subsp noeana and Its Secondary Metabolites
Ertas, Abdulselam; Goeren, AHMET CEYHAN; Hasimi, Nesrin; Tolan, Veysel; Kolak, Ufuk (2015-01-01)The aim of the present study was to determine the chemical structures of the isolated compounds, the essential oil and fatty acid compositions of Mentha longifolia subsp. noeana with their biological activities. Ursolic ... -
In vitro biological activities and fatty acid profiles of Pistacia terebinthus fruits and Pistacia khinjuk seeds
Hacibekiroglu, IŞIL; Yilmaz, Pelin Koseoglu; Hasimi, Nesrin; Kilinc, Ersin; Tolan, Veysel; Kolak, Ufuk (2015-03-04)This study reports in vitro anticholinesterase, antioxidant and antimicrobial effects of the n-hexane, dichloromethane, ethanol and ethanol-water extracts prepared from Pistacia terebinthus L. fruits and Pistacia khinjuk ... -
Indole Alkaloids from Vinca major and V. minor Growing in Turkey
Bahadori, FATEMEH; Topcu, Gulacti; Boga, Mehmet; Turkekul, Ayla; Kolak, Ufuk; Kartal, MURAT (2012-06-01)A new indole alkaloid, 11-hydroxypolyneuridine, was isolated from Vinca major subsp. major L. and the known indole alkaloids vallesiachotamine and isovallesiachotamine from Vinca minor L. This is the first report on the ... -
Investigation of Anticholinesterase Activity of a Series of Salvia Extractsand the Constituents of Salvia staminea
Topçu, Gülaçtı; Hatipoğlu, Seda Damla; Boğa, Mehmet; Kolak, Ufuk; Öztürk, Mehmet; Dirmenci, Tuncay; Bahadori, Fatemeh; Bütün, Burcu (2013-03-01) -
Method Validation for the Quantitative Analysis of Aflatoxins (B1, B2, G1, and G2) and Ochratoxin A in Processed Cereal-Based Foods by HPLC with Fluorescence Detection
Gazioglu, IŞIL; Kolak, Ufuk (2015-07-01)Modified AOAC 991.31 and AOAC 2000.03 methods for the simultaneous determination of total aflatoxins (AFs), aflatoxin B1, and ochratoxin A (OTA) in processed cereal-based foods by RP-HPLC coupled with fluorescence detection ...
