Browsing by Author "Kocyigit, ABDÜRRAHİM"
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A new approach to recurrent pregnancy losses: anti-cardiolipin-specific peptide screening with phage display technique
BULUT, HURİ; Kocyigit, ABDÜRRAHİM; Yuksel, B.; Şahin, Deniz (2017-09-01) -
Ankaferd hemostat induces DNA damage, apoptosis and cytotoxic activity by generating reactive oxygen species in melanoma and normal cell lines
Malkan, Umit Yavuz; Guler, ERAY METİN; Kocyigit, ABDÜRRAHİM; HAZNEDAROĞLU, İBRAHİM CELALETTİN (2017-01-01)Although, Ankaferd hemostat (Ankaferd Blood Stopper, ABS) could be utilized successfully as hemostatic agent, studies demonstrated that it has cytotoxic effects on cells. However, the mechanism(s) of this effect has not ... -
Antigenotoxic and antioxidant potentials of newly derivatized compound naringenin-oxime relative to naringenin on human mononuclear cells
Taskin, Abdullah; Bahadori, FATEMEH; Turkkan, Baki; Dikilitas, Murat; Koyuncu, Ismail; Kocyigit, ABDÜRRAHİM (2016-01-02)We investigated antigenotoxic and antioxidative effects of newly derivatized compound naringenin-oxime (NG-Ox) compared to its mother compound naringenin (NG) against oxidative damage induced by hydrogen peroxide (HP) in ... -
Antioxidant and anticancer effect of Artemisia absinthium extract on colon and endometrium adenocarcinoma cells
Koyuncu, I.; GULER, ERAY METİN; Kocyigit, ABDÜRRAHİM; Yuksekdag, O.; Kirmit, A. (2016-09-01) -
Antioxidant and toxicological in-vivo and in-vitro examination of licorice extract
Guler, E. M.; Bektay, MUHAMMED YUNUS; Topcu, GÜLAÇTI; Bayindir, NİHAN; Uckaya, FATİH; Esrefoglu, MUKADDES; Kocyigit, ABDÜRRAHİM (2016-09-01) -
Are the oxidative stress levels in the tumor center and tumor boundary different from those in healthy tissue?
Guler, Eray Metin; Senturk, Erol; Çelik, İsmail; Kocyigit, ABDÜRRAHİM; Dogan, Remzi; Ozturan, Orhan; Tugrul, Selahattin; Yenigun, Alper (2021-04-03) -
Assessment of the effectiveness of cyclosporine nasal spray in an animal model of allergic rhinitis
Kocak, Ilker; Yildirim, YAVUZ SELİM; AYDIN, Mehmet Serif; Kocyigit, ABDÜRRAHİM; Senturk, EROL; Esrefoglu, MUKADDES; Guler, ERAY METİN; Ozturan, ORHAN; Dogan, REMZİ (2018-01-01)The aim of this study is to show if cyclosporine has an antiallergic role in a rat model of ovalbumin-induced allergic rhinitis. The 54 rats were divided into six equal groups. The first group was a negative control group ... -
Association of parity with osteoprotegerin levels and atherosclerosis
Vural, Mehmet; Toy, Harun; Camuzcuoglu, Hakan; Cece, Hasan; Yildiz, Sema; Eren, Mehmet Ali; Kocyigit, ABDÜRRAHİM (2013-06-01)Purpose Association of serum osteoprotegerin (OPG) levels and cardiovascular disorders has been shown previously. The aim of this observational study was to investigate the relationship between parity, OPG and carotid ... -
Beta-globin gene mutations in children with beta-thalassemia major from Sanliurfa province, Turkey
Aycicek, Ali; Kocyigit, ABDÜRRAHİM; Dilmec, Fuat; Bilinc, Hasan; Ozdemir, Zeynep Canan; Koc, Ahmet (2011-12-01)Objective: The prevalence of (beta-thalassemia in Sanhurfa province, Turkey is reported to be 2.6%-3.7%, whereas nation-wide the frequency of beta-thalassemia is 2%. This study aimed to identify the most frequent ... -
Can Oxidative Stress Parameters Be Used as Biomarkers for the Discrimination of Malignant Head and Neck Tumors
KESKIN, Siddika; HAFIZ, Aysenur Meric; Dogan, REMZİ; Ozturan, ORHAN; Kocyigit, ABDÜRRAHİM; TUGRUL, Selahattin (2016-05-01)Objective: In this study the authors have investigated oxidative stress parameters in sera and tissues, and evaluated their significance for the differentiation of malignant and benign tumors. -
Cathelicidin (LL-37) and human 2-defensin levels of children with post-infectious bronchiolitis obliterans
Uyan, Zeynep Seda; Cakir, ERKAN; Torun, EMEL; Kocyigit, ABDÜRRAHİM; GÖKDEMİR, YASEMİN; GEDIK, Ahmet Hakan; Karakoc, Fazilet; Ersu, Refika; Karadag, Bulent (2017-03-01)IntroductionThe antimicrobial peptides (AMPs) human -defensins and cathelicidin (LL-37) are key factors in innate and adaptive immune responses of the respiratory tract and play an important role in many respiratory diseases. ... -
Comparison of the biochemical and radiological criteria for lumbar disc degeneration
Papaker, Meliha Gundeg; Seyithanoglu, MEHMET HAKAN; ABDALLAH, Anas; DÜNDAR, Tolga; Kocyigit, ABDÜRRAHİM; Ozer, Omer Faruk; Kitis, SERKAN (2018-09-01)Background: The relationship between radiological degeneration criteria on lumbar magnetic resonance imaging (MRI) and both the keratan sulfate (KS) and chondroitin sulfate (ChS) levels was examined in disc material taken ... -
Comparison of the efficacy of multiple antioxidant and hyperbaric oxygen treatments in the prevention of ischemia and necrosis of local random McFarlane skin flap.
Metin Guler, Eray; Esrefoglu, Mukaddes; Bayindir, Nihan; Kocyigit, ABDÜRRAHİM; Dogan, Remzi; Ozturan, Orhan; Yenigun, Alper; Mirasoglu, Bengisu Oroglu (2021-02-26) -
Curcumin induce DNA damage and apoptosis through generation of reactive oxygen species and reducing mitochondrial membrane potential in melanoma cancer cells
Guler, ERAY METİN; Kocyigit, ABDÜRRAHİM (2017-01-01)Melanoma is the most malignant skin cancer. Curcumin has shown to have therapeutic effects when used in the treatment of malignant diseases. However, the precise molecular mechanisms of its action are not fully elucidated. ... -
Curcumin induced cytotoxicity by oxidative stress mediated DNA damage and apoptosis in mouse B16F10 melanoma cells
Kocyigit, ABDÜRRAHİM; Guler, Eray M.; KARATAS, Ersin (2015-08-01) -
Cytotoxic, genotoxic and apoptotic activities of carvacrol from Thymus vulgaris on the human adenocarcinoma gastric cells
KARAKAS, Ersin; Guler, ERAY METİN; Kiziltan, HURİYE ŞENAY; GUNES-BAYIR, Ayse; Kocyigit, ABDÜRRAHİM (2015-08-01) -
Dexpanthenol and ascorbic acid ameliorate colistin-induced nephrotoxicity in rats.
Aslan, T; Durdu, B; Cakir, A; Guler, E M; Kocyigit, ABDÜRRAHİM; Hakyemez, I N; Coban, G; Celikten, M; Huseyinbas, O; Gulgec, A S; Dundar, T (2021-01-01) -
Diagnostic potential of Brucella melitensis Rev1 native Omp28 precursor in human brucellosis
Koyuncu, Ismail; Karsen, Hasan; Kirmit, Adnan; Kocyigit, ABDÜRRAHİM; Ozer, Ahmet; SELEK, Sahabettin (2018-01-01)Serologic tests for brucellosis aim to detect antibodies produced against membranous lipopolysaccharide of bacteria. Diagnostic use of this method is limited due to false positiveness. This study evaluates an alternative ... -
Dimethoate-induced oxidative stress and DNA damage in Oncorhynchus mykiss
Can, Canan; Kocyigit, ABDÜRRAHİM; Bilinc, Hasan; Taskin, Abdullah; Dikilitas, Murat; Dogan, Demet (2011-06-01)The present study was conducted in order to investigate pro-oxidant activity of dimethoate in liver and brain tissues following sublethal pesticide exposure for 5, 15 and 30 d by using SOD, GPx, CAT enzyme activities and ... -
DNA damage and oxidative status in newly diagnosed, untreated, dipper and non-dipper hypertensive patients
ELBASAN, Zafer; OZALTUN, Betul; SEKER, Taner; KOYUNSEVER, Nermin Yildiz; SAHIN, Durmus Yildiray; GUR, Mustafa; Kocyigit, ABDÜRRAHİM; CAYLI, Murat (2013-02-01)DNA damage occurs more often in hypertensive patients than in non-hypertensive individuals. We sought to investigate lymphocyte DNA damage and total antioxidant status (TAS) levels in patients with dipper hypertension (DH) ...
