Browsing by Author "Gonel, Ataman"
Assessment of the antiproliferative and apoptotic roles of sulfonamide carbonic anhydrase IX inhibitors in HeLa cancer cell line Gonel, Ataman; Yuksekdag, Ozgur; KOÇYİĞİT, ABDÜRRAHİM; Durgun, Mustafa; Koyuncu, Ismail; Supuran, Claudiu T. (2019-01-01)Carbonic anhydrase IX (CA IX) has recently been validated as an antitumor/antimetastatic drug target. In this study, we examined the underlying molecular mechanisms and the anticancer activity of sulfonamide CA IX ...
Selective inhibition of carbonic anhydrase-IX by sulphonamide derivatives induces pH and reactive oxygen species-mediated apoptosis in cervical cancer HeLa cells Koyuncu, Ismail; Supuran, Claudiu T.; Durgun, Mustafa; Temiz, Ebru; Gonel, Ataman; KOÇYİĞİT, ABDÜRRAHİM (2018-12-01)Selective inhibition with sulphonamides of carbonic anhydrase (CA) IX reduces cell proliferation and induces apoptosis in human cancer cells. The effect on CA IX expression of seven previously synthesised sulphonamide ...
The evaluation of antioxidant and anticancer effects of Lepidium Sativum Subsp Spinescens L. methanol extract on cancer cells Koyuncu, Ismail; ÇAĞLAR, HİFA GÜLRU; Gonel, Ataman; Yilmaz, Mustafa Abdullah; Bektas, Ibrahim; Selek, Sahabettin; Akyuz, ENES (2018-01-01)