Browsing by Author "Angeli, A"
Now showing items 1-3 of 3
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Design, synthesis and biological activity of selective hCAs inhibitors based on 2-(benzylsulfinyl)benzoic acid scaffold.
De, Filippis; Carradori, S; Secci, D; De, Monte; Maccallini, C; Supuran, CT; Guglielmi, P; Angeli, A; Akdemir, ATİLLA; Cirilli, R; Amoroso, R; Rotondi, G (2019-12-01)A large library of derivatives based on the scaffold of 2-(benzylsulfinyl)benzoic acid were synthesised and tested as atypical inhibitors against four different isoforms of human carbonic anhydrase (hCA I, II, IX and XII, ... -
Development of Thiazolidinones as Fungal Carbonic Anhydrase Inhibitors.
Carradori, S; Angeli, A; Demir-Yazıcı, K; Grande, R; Güzel-Akdemir, Ö; Akdemir, ATİLLA; Supuran, CT (2020-04-22)In our efforts to find new and selective thiazolidinone-based anti-Candida agents, we synthesized and tested 26 thiazolidinones against several Candida spp. and Gram-positive and Gram-negative bacteria. The compounds ... -
Novel Indole-Based Hydrazones as Potent Inhibitors of the α-class Carbonic Anhydrase from Pathogenic Bacterium <i>Vibrio cholerae</i>.
Demir-Yazıcı, K; Akdemir, Atilla; Supuran, Ct; Angeli, A; Güzel-Akdemir, Ö (2020-04-29)Due to the increasing resistance of currently used antimicrobial drugs, there is an urgent problem for the treatment of cholera disease, selective inhibition of the α-class carbonic anhydrases (CA, EC 4.2.1.1) from the ...