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https://hdl.handle.net/20.500.12645/18146

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Browsing Tezler by Subject "Adipoz doku = Adipose tissue"

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    Lipödemli hastalarda gövde stabilizasyon egzersizlerinin postüral stabiliteye etkisi
    (Bezmialem Vakıf University, 2019) Demircan, Güler; Kostanoğlu, Alis
    The aim of our study is to investigate the effect of trunk stabilization exercises in addition to active range of motion exercises on body composition, pain, edema, trunk endurance, functional capacity and postural stability. Lipoedema is a chronic, progressive adipose tissue disorder that is mostly seen as a symmetrical growth of the hips and legs, affecting women. The study is included 32 female patients with a mean age of 53,06 ± 7,92 who were diagnosed as upper and lower leg lipoedema. The subjects were divided into two groups as experimental (n = 17) and control (n = 15) groups. The physiotherapy program of the control group consisted of active range of motion exercises and the physiotherapy program of the experimental group consisted of trunk stabilization exercises in addition to the active range of motion exercises. After the demographic data of all cases were recorded, the extremity volume (circumference measurement), body composition analysis, trunk endurance, pain (Visual Analog Scale), postural stability (Biodex Balance System®) and functional capacities (6 Minutes Walking Test) were evaluated. After the six-week treatment program, all evaluations were repeated. SPSS (SPSS 21.0) program was used for statistical analysis of the data. For all analyzes, the level of significance was accepted as p <0.05. As a result of our study, a statistically significant improvement was found in pain, extremity circumference measurement and 6 minutes walking test values in both groups. In addition, body composition, trunk endurance and postural stability were found significantly different in the experimental group. Considering the intergroup evaluation; postural stability, body composition, trunk endurance, extremity circumference measurement, walking distance values were found statistically superior to the experimental group. There was no significant difference between the two groups in pain scores. In our study planned to compare the effects of body stabilization exercises on postural stability in patients with lower and upper leg lipoedema in addition to active range of motion exercise program, it was concluded that active range of motion exercise program was sufficient to reduce pain in lower and upper leg lipoedema patients. It was concluded that trunk stabilization exercises in addition to active range of motion exercises program are more effective method to improve the body composition, trunk endurance and postural stability in reducing the volume of the limb and increasing the functional capacity.
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    Sıçanlarda silikon implant etrafında kapsül oluşumuna otojen yağ dokudan elde edilen mezenkimal kök hücrelerin etkisinin araştırılması: Sıçan modelinde deneysel çalışma / An experimental study in a rat model: The research of the effect of mesenchymal stem cells derived from autogenous fat tissue to the capsule formation around silicone implants
    (Bezmialem Vakıf University, 2011) YOĞUN, Fatma Nilay; YRD. DOÇ. DR. MEHMET VELİ KARAALTIN
    In this study, the effect of mesenchymal stem cells that derived from autogenous fat tissue to the capsule formation around silicone implants has been searched.16 Wistar Albino rats, weight of 270-310 gr, were used for the study. The subjects are divided into equal groups as experiment group (Group II) and control group (Group I). Subcutaneous silicone implants was placed in the pectoral area of all rats in both groups by opening a pouch for implant. While it was not used an additional therapy for Group I, it was injected a suspension containing 40 million cells / cc to the pouch where the silicone implant placed in Group II. All implants excised at the postoperative 8th week from both groups. Capsule formation removed totally and took histopathological examination.Samples were examined by histology specialist: Morphometric evaluation with volumetric measurement of capsules thickness, evaluation of the amount of collagen-procollagen, light microscopy with Masson Trichrome dyeing. In morphometric evaluation of capsule thickness there was a significant difference between Group I and Group II (p<0,032). In Group II the amount of procollagen- collagen was lower than Group I. In light microscopy neoangiogenesis in Group II higher than Group I.In this study it is founded that the use of 40 million cells/cc mesenchymal stem cells reduce the capsule formation around the silicone implant and the silicone implant does not form foreign body reaction.